LOINC
Version 2.67

76544-6Breast cancer 10-year risk of distant recurrence score Calculated by ProsignaActive

Term Description

The 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes: 1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years. This term was created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone.
Source: Regenstrief LOINC

Fully-Specified Name

Component
Breast cancer 10Y risk of distant recurrence score
Property
Score
Time
Pt
System
^Patient
Scale
Qn
Method
Calculated.Prosigna

Additional Names

Short Name
Brst ca 10Y dist recur score Prosigna
Display Name
Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna [Score]

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.63
Change Reason
Order_Obs: changed from 'observation' to 'both' to reflect that the LOINC code can also be used as an order code.
Order vs. Observation
Both

Formula (Readable)

Calculated using a Cox model that includes coefficients for the gene expression assay results, proliferation score, and gross tumor size.

Member of these Panels

LOINC Long Common Name
76546-1 Breast cancer 10-year risk of distant recurrence panel by Prosigna

Language Variants Get Info

zh-CNChinese (CHINA)
乳腺癌远处转移 10 年风险评分:评分:时间点:^患者:定量型:计算法.Prosigna
fr-FRFrench (FRANCE)
Breast cancer 10Y risk of distant recurrence score:Score:Pt:^Patient:Qn:Calculated.Prosigna
it-ITItalian (ITALY)
Tumore della mammella, rischio 10 anni di recidive tumorali, punteggio:Punteggio:Pt:^Paziente:Qn:Calcolato.Prosigna
es-ESSpanish (SPAIN)
Ratio del riesgo de recurrencia a 10 años en el cáncer de mama:Puntuación:Punto temporal:^paciente:Qn:Calculado por Prosigna

Example Units

Unit Source
{score} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76544-6