LOINC
Version 2.73

76688-1Alpha-1-acid glycoprotein/Creatinine [Mass Ratio] in UrineActive

Term Description

The alpha-1-acid glycoprotein/creatinine ratio is used to monitor the effectiveness of renal dialysis. Determinations are expressed in /mg creatinine to compensate for variations in urine concentration.
Source: Regenstrief LOINC

Part Descriptions

LP15755-9   Alpha-1-acid glycoprotein
Alpha-1-acid glycoprotein (AGP or orosomucoid ORM), is an acute phase reactant glycoprotein found in a number of conditions, and considered a natural anti-inflammatory and immunomodulatory agent, particularly with respect to its anti-neutrophil and anti-complement activity. Serum levels increase in response to systemic tissue injury, inflammation or infection. Expression of the AGP gene is regulated through major mediators (glucocorticoids and a cytokine network involving mostly interleukin-1β (IL-1β), tumour necrosis factor-α (TNFα), interleukin-6 and IL-6 related cytokines). [PMID:11058758] AGP is used to monitor acute-phase proteins related to inflammatory conditions like RA, Crohn's disease, injuries, burns, malignant neoplasms, and inflammation or infection conditions of unknown etiology. Low serum concentrations may be due to chronic liver diseases or to increased excretion of the protein as in nephritic syndrome.(Lab Partner1)[PMID:11058758] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Regenstrief LOINC, PMID: 11058758

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component
Alpha-1-acid glycoprotein/Creatinine
Property
MRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
A1acid Glycoprotein/Creat Ur
Display Name
Alpha-1-acid glycoprotein/Creatinine (U) [Mass ratio]
Consumer Name Alpha
Alpha-1-acid glycoprotein/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.52
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
Alpha-1-酸性糖蛋白/肌酐:质量比率:时间点:尿液:定量型:
nl-NLDutch (Netherlands)
alfa-1-zure glycoproteïne/creatinine:massaverhouding:moment:urine:kwantitatief:
et-EEEstonian (Estonia)
Alfa-1-happeline glükoproteiin/kreatiniin:MRto:Pt:U:Qn:
fr-BEFrench (Belgium)
Alpha-1 glycoprotéine acide/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif:
fr-CAFrench (Canada)
Alpha-1 glycoprotéine acide/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif:
fr-FRFrench (France)
Orosomucoïde/créatinine:Masse ratio:Ponctuel:Urine:Numérique:
it-ITItalian (Italy)
Alfa-1-Glicoproteina acida/Creatinina:MRto:Pt:Urine:Qn:
ru-RURussian (Russian Federation)
Альфа-1-Кислый гликопротеин/Креатинин:МассОтн:ТчкВрм:Моча:Колич:
es-MXSpanish (Mexico)
Glicoproteína ácida alfa-1 / Creatinina:Relación de masa:Punto temporal:Orina:Cuantitativo:
es-ESSpanish (Spain)
Alfa1 glicoproteína ácida/Creatinina:Relacion de Masa:Punto temporal:Orina:Qn:
tr-TRTurkish (Turkey)
Alfa-1-Asit glikoprotein/Kreatinin:KütlOr:Zmlı:İdrar:Kant:

Example Units

Unit Source
mg/g{creat} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76688-1