767-4

Neutrophils.hypersegmented/Leukocytes in Blood by Manual count

Active

Part Descriptions

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LP17593-2   Neutrophils.hypersegmented
Hypersegmented neutrophils are neutrophils with 5 or more nuclear lobes. They are often seen in disorders of nuclear maturation and are thought to be pathognomonic of the class of anemias called megaloblastic anemias. Some studies, however, have strongly associated neutrophil hypersegmentation with iron deficiency anemia.
One of the earliest changes in the megaloblastic processes is the appearance of these hypersegmented neutrophils. Because of the short life-span of neutrophils, these abnormal cells characteristically appear even before the onset of anemia [2]. However, such neutrophils are not seen in the other classes of anemias, which incidently are far more common than megaloblastic anemias. It is of note that pernicious anemia is a type of megaloblastic anemia, and as such, may show hypersegemented neutrophils. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name

Neutrophils.hypersegmented/Leukocytes:NFr:Pt:Bld:Qn:Manual count

Long Common Name

Neutrophils.hypersegmented/Leukocytes in Blood by Manual count

Short Name

Neuts Hyperseg NFr Bld Manual

Display Name

Neutrophils.hypersegmented/Leukocytes Manual cnt (Bld)

Consumer Name Alpha Get Info

Neutrophils.hypersegmented/White Blood Cells, Blood

Part Model Get Info

• Component

  Neutrophils.hypersegmented/Leukocytes
  LP445495-7

  • Analyte

    Neutrophils.hypersegmented/Leukocytes
    LP445495-7

    • Component Numerator

      Neutrophils.hypersegmented
      LP17593-2

      • Component Numerator Core

        Neutrophils.hypersegmented
        LP17593-2

      • Component Numerator Core Suffix

        NULL
         

    • Component Denominator

      Leukocytes
      LP157588-7

      • Component Denominator Core

        Leukocytes
        LP157588-7

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  NFr
  LP6838-9

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  Bld
  LP7057-5

  • System Core

    Bld
    LP7057-5

  • Super System

    NULL
     

• Scale

  Qn
  LP7753-9

• Method

  Manual count
  LP6377-8

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Common Test Rank Get Info

7304

Language Variants Get Info

Related Names

• Blood
• HEMATOLOGY/CELL COUNTS
• Hyperseg
• Hyper-Seg
• Hypersegs
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Manl
• Neut
• Neutr
• Neutrophil
• Neuts Hyperseg
• Number Fraction
• Percent
• PMN
• PNM
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=767-4

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.