77169-1

cycloSPORINE [Mass/volume] in Blood --1 hour post dose

Active

Part Description

LP16098-3 cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. PMID: 19545653 Source: Regenstrief LOINC, PMID: 19545653

LOINC Names Get Info

Fully-Specified Name: cycloSPORINE^1H post dose:MCnc:Pt:Bld:Qn:
Long Common Name: cycloSPORINE [Mass/volume] in Blood --1 hour post dose
Short Name: cycloSPORINE 1h p Bld-mCnc
Display Name: cycloSPORINE 1 Hr post dose (Bld) [Mass/Vol]
Consumer Name Alpha Get Info: cycloSPORINE 1 hr after dose, Blood

Part Model Get Info

Component
cycloSPORINE^1H post dose
LP307879-9
- Analyte
  cycloSPORINE
  LP16098-3
  - Component Numerator
    cycloSPORINE
    LP16098-3
    - Component Numerator Core
      cycloSPORINE
      LP16098-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  1H post dose
  LP34580-8
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.52
Last Updated: Version 2.66 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cyklosporin^1 hodina po podání dávky:Hmotnostní koncentrace:Časový bod:Krev:Kvantitativní:
el-GR	Greek (Greece)	Κυκλοσπορίνη^1 ώρα κατόπιν δόσης:MCnc:Pt:Αίμα:Qn: Synonyms: 1 ώρα κατόπιν δόσης DRUG/TOX MCnc Pt Qn Αίμα κατόπιν δόσης Κυκλοσπορίνη
es-ES	Spanish (Spain)	Ciclosporina^1H pos dosis:Concentración de masa:Punto temporal:Sangre:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	cycloSPORINE ^1H después de la dosis:Concentración de masa:Punto temporal:Sangre:Cuantitativo:
et-EE	Estonian (Estonia)	Tsüklosporiin^1 tund pärast manustamist:MCnc:Pt:B:Qn: Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA	French (Canada)	Cyclosporine^1 h post dose:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-FR	French (France)	Ciclosporine^T01h après administration:Masse/Volume:Ponctuel:Sang:Numérique:
fr-BE	French (Belgium)	Cyclosporine^1 h post dose:Concentration de masse:Temps ponctuel:Sang:Quantitatif: Synonyms: Post dose. 1H
it-IT	Italian (Italy)	Ciclosporina^1h post dose:MCnc:Pt:Sangue:Qn: Synonyms: 1 ora dopo dose Concentrazione di Massa dopo dose Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
nl-NL	Dutch (Netherlands)	ciclosporine^60 min na dosis:massa/volume:moment:bloed:kwantitatief: Synonyms: 1 uur na dosis
pl-PL	Polish (Poland)	Cyklosporyna^1h po dawce:stężenie masowe:punkt w czasie:krew:ilościowy: Synonyms: 1 godzina po podaniu dawki po podaniu dawki
ru-RU	Russian (Russian Federation)	Циклоспорин^1 час после дозы:МассКонц:ТчкВрм:Кр:Колич: Synonyms: Количественный Кровь Массовая концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Siklosporin^1Sa snr doz:KütlKons:Zmlı:Kan:Kant:
zh-CN	Chinese (China)	环孢菌素^在剂量药物之后1小时:质量浓度:时间点:全血:定量型: Synonyms: 1Hr之后于剂量物质;1Hr之后于剂量药物;1小时之后于剂量物质;1小时之后于剂量药物;60Min之后于剂量物质;60Min之后于剂量药物;60分钟之后于剂量物质;60分钟之后于剂量药物;在剂量物质之后1Hr;在剂量物质之后1小时;在剂量物质之后60Min;在剂量物质之后60分钟;在剂量药物之后1Hr;在剂量药物之后60Min;在剂量药物之后60分钟 XXX刺激 - 在...之后一剂物质一剂药物之后于... 之后于剂量物质;之后于剂量药物;在剂量物质之后剂量物质可用数量表示的;定量性;数值型;数量型;连续数值型标尺在...以后在后时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 环孢霉素A; 山地明环孢灵; 环孢多肽A; 环孢素; 赛斯平; 环孢菌素; 环孢菌素A; 环孢素A;山地明;环孢多肽;环孢抑制剂;环孢灵;环孢霉素;环孢霉素A;环孢素;Cyclosporine;Cyclosporin; Restasis; Cyclosporine A; cyclosporin A; Antibiotic S 7481F1; 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonameth 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血;血液

Example Units

Unit	Source
ug/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.