77254-1

Microalbumin/Creatinine [Ratio] in 24 hour Urine by Detection limit <= 1.0 mg/L

Active

Term Description

Measures the albumin excretion in urine to aid in the early detection of kidney disease (and increased risk of cardiovascular events) for patients with diabetes. Normal 24 hour urine albumin excretion is less than 30 mg/day in adults. 24-hour urine excretion results between 30-300 mg/day are defined as microalbuminuria (MAU) which may occur with kidney damage.
Source: Regenstrief LOINC

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LP6118-6   Albumin
A non-glycosylated protein that is synthesized in the liver parenchymal cells, regulated by colloid osmotic pressure from interstitial fluid surrounding hepatocytes, and catabolized in nearly all organs. Albumin comprises >50% of plasma proteins in plasma, CSF and urine, and therefore is a key contributor to intravascular oncotic pressure and regulating fluid concentration in tissues. Albumin also binds and transports a variety of endogenous substances and medications. Serum albumin measurement is a reflection of hydration and nutritional status, blood oncotic pressure, liver and kidney function, and other chronic diseases, and the ratio of albumin in the CSF and serum can be used to evaluate blood brain barrier disorders. [Tietz] Urine albumin of less than 30 mg/day is considered normal. Microalbuminuria is defined as urine albumin of 30-300 mg/day and is an early sign of kidney damage from disorders such as diabetes or hypertension. Albuminuria is urine albumin >300 mg/day and is associated with overt kidney disease. PMID: 25512779 Source: Regenstrief LOINC

LP70454-1   Detection limit <= 1.0 mg/L
Limit of detection is the lowest analyte concentration at which detection is feasible for the assay method. [PMCID: 2556583] Source: Regenstrief LOINC

Fully-Specified Name

Component

Albumin/Creatinine

Property

Ratio

Time

24H

System

Urine

Scale

Qn

Method

Detection limit <= 1.0 mg/L

Additional Names

Short Name

Microalbumin/Creat 24h Ur DL<=1mg/L-Rto

Display Name

Albumin/Creatinine DL <= 1.0 mg/L (24H U) [Ratio]

Consumer Name Alpha Get Info

Albumin/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.52

Last Updated

Version 2.54

Order vs. Observation

Both

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 1 day
• 24 hours
• 24HR
• Alb
• Chemistry
• CR
• Crea
• Creat
• DL&lt
• =1 mg/L
• Kidney
• Left
• Levo
• MA
• Malb
• Micro albumin
• Microalbumin
• Nephrology
• Protein.albumin
• QNT
• Quan
• Quant
• Quantitative
• Ratios
• Renal
• Rto
• UA
• UCr
• UR
• Urn

Example Units

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.