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Term Description

This term was created for, but not limited in use to, the submitter's Roche, STAGO, STACHROM TAFI test kit, using a synthetic chromogenic substrate method.

Part Description

LP190644-7   Thrombin activatable fibrinolysis inhibitor
TAFI (Thrombin Activatable Fibrinolysis Inhibitor) is a glycoprotein of a molecular weight of approximately 60,000 daltons and it belongs to the metalloprotease family, synthesized in the liver, and circulates in blood as a proenzyme without biological activity. TAFI is also called procarboxypeptidase U (CPU), procarboxypeptidase R (CPR), and plasma procarboxypeptidase B (CPB), and provides an essential link between fibrinolysis and coagulation cascade. Activated TAFI protects the fibrin clot against lysis. Defects in thrombin generation directly impact the protection of clots against lysis, thus defects in activation of TAFI may add to the severity of bleeding disorders. On the other hand, an increased activation of TAFI due to an increased rate of thrombin generation, may lead to thrombotic disorders. TAFI may also have an important function in the regulation of inflammation, wound healing and blood pressure. PMID: 15015228 PMID: 17008302 Elevated TAFI levels may form a mild risk factor for venous thrombosis. PMID: 10779431 Source: Regenstrief LOINC, PMID: 15015228

LOINC Names Get Info

Fully-Specified Name
Thrombin activatable fibrinolysis inhibitor:ACnc:Pt:PPP:Qn:Chromo
Long Common Name
Thrombin activatable fibrinolysis inhibitor [Units/volume] in Platelet poor plasma by Chromogenic method
Short Name
TAFI PPP Chro-aCnc
Display Name
Thrombin activatable fibrinolysis inhibitor Chromogenic method Qn (PPP)
Consumer Name Alpha Get Info
Thrombin activatable fibrinolysis inhibitor, Blood

Part Model Get Info

  • Component
    Thrombin activatable fibrinolysis inhibitor
    LP190644-7
    • Analyte
      Thrombin activatable fibrinolysis inhibitor
      LP190644-7
      • Component Numerator
        Thrombin activatable fibrinolysis inhibitor
        LP190644-7
        • Component Numerator Core
          Thrombin activatable fibrinolysis inhibitor
          LP190644-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    ACnc
    LP6773-8
  • Time
    Pt
    LP6960-1
  • System
    PPP
    LP7494-0
    • System Core
      PPP
      LP7494-0
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Chromo
    LP6256-4

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.52 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Trombinem aktivovatelný inhibitor fibrinolýzy:Arbitrární koncentrace:Časový bod:Plazma chudá na trombocyty:Kvantitativní:Chromogenní (enzymatický) test
el-GRGreek (Greece)Ενεργοποιούμενος από τη θρομβίνη αναστολέας της ινωδόλυσης:ACnc:Pt:PPP:Qn:Chromo
Synonyms: ACnc Chromo COAG PPP Pt Qn Ενεργοποιούμενος από τη θρομβίνη αναστολέας της ινωδόλυσης
es-ESSpanish (Spain)Inhibidor tisular del activador del plasminógeno:Concentración arbitraria:Punto temporal:Plasma pobre en plaquetas:Qn:Cromogénico ( Enzima)
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Inhibidor de la fibrinólisis activable por trombina:Concentración arbitraria:Punto temporal:Plasma pobre en plaquetas:Cuantitativo:Cromogénico (enzima)
fr-FRFrench (France)Inhibiteur de fibrinolyse activable par la thrombine:Arbitraire/Volume:Ponctuel:Plasma pauvre en plaquettes:Numérique:Technique chromogénique
it-ITItalian (Italy)Inibitore della fibrinolisi attivabile dalla trombina:ACnc:Pt:PPP:Qn:Cromo
Synonyms: Concentrazione Arbitraria Cromogenico (Enzima) Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione TAFI
nl-NLDutch (Netherlands)trombine activeerbare fibrinolyse inhibitor:eenheid/volume:moment:plaatjesarm plasma:kwantitatief:chromogeen
Synonyms: coagulatiemethode
tr-TRTurkish (Turkey)Trombin aktiveedebilen fibrinoliz inhibitörü:SçKons:Zmlı:TFkP:Kant:Kromo
zh-CNChinese (China)凝血酶激活的纤溶抑制物:任意型浓度:时间点:贫血小板血浆:定量型:凝血因子酶学测定法
Synonyms: 乏血小板血浆;Platelet poor plasma;PPP 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 凝血因子 凝血因子发色测定方法;凝血因子发色测定法;凝血因子酶学测定方法;发色法;发色测定方法;发色测定法;显色法;显色测定方法;显色测定法;酶学法;酶学测定方法;酶学测定法;酶法 凝血酶激活的纤溶（纤维蛋白溶解）抑制物（抑制剂、抑制因子）;TAFI;凝血酶可激活型纤溶抑制物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抑制因子 抑制物 抑制物质 时刻;随机;随意;瞬间 纤维蛋白酶

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77683-1