Version 2.77

Term Description

Because Toscana virus is a known etiologic agent of meningitis, meningoencephalitis, and encephalitis, cerebrospinal fluid (CSF) may be tested. Specific antibodies for IgM are present during the acute phase of the Toscana Virus infection, while the presence of specific IgG antibodies in the absence of IgM indicates a previous infection. Cross reactions cannot be excluded with other correlated serotypes of Phlebovirus such as Sicily and Naples. This term was created for, but not limited in use to, the submitter's Diesse ENZYWELL TOSCANA VIRUS IgG/IgM test kit..
Source: Regenstrief LOINC

Part Descriptions

LP190784-1   Toscana virus Ab.IgG
The Toscana virus (TOSV) belongs to the Phlebovirus genus of the Bunyaviridae family, and is an arthropod-borne virus transmitted to humans by Phlebotomus spp sandflies. The Toscana virus infection is characterized by fever, strong headache, and meningitis, or meningoencephalitis. TOSV is the major cause of aseptic meningitis (95%) and meningoencephalitis (4.5%) and influenza-like illness during the summer season. Some unusual clinical manifestations due to TOSV with severe sequelae, such as ischemic complications and hydrocephalus, have been reported. TOSV represents an important emerging pathogen and it is being investigated in several countries on the Mediterranean basin, including Italy, France, Spain, Portugal and Cyprus. Phylogenetic analysis has distinguished two genotypes of TOSV, A and B. The first is circulating mainly in Italy and the second in Spain, indicating a different geographic distribution possibly related to the vector. There is no treatment for TOSV infection except for supportive therapy. PMID: 20517492 Source: Regenstrief LOINC, PMID: 20517492

LP190786-6   Toscana virus
Toscana virus (TOSV) was identified in 1971 in central Italy from sandflies Phlebotomus perniciosus and Phlebotomus perfiliewi PMID: 24175218. TOSV belongs to the family Phenuiviridae, genus Phlebovirus [NCBI Taxonomy: 11590)]. TOSV is a serotype of the species Sandfly fever Naples virus PMID: 24175218. TOSV is the only neurotropic sandfly phlebovirus typically causing meningitis and encephalitis. Additional neuroinvasive manifestations such as Guillain-Barré syndrome, hydrocephalus, myositis, fasciitis, polymyeloradiculopathy, deafness, and facial paralysis, have been reported. Toscana virus broadly circulates in in European Mediterranean basin and Northern Africa PMID: 32878929. Source: Regenstrief LOINC

LP190786-6   Toscana virus
The Toscana virus (TOSV) belongs to the Bunyaviridae family whose genome is made of three negative single-stranded RNA segments. There are two genotypes of TOSV: A, found mainly in Italy, and B, occurring mainly in Spain. The distribution of the two genotypes may indicate the involvement of different vectors. Infection by TOSV is most prevalent in Italy and Spain in the summer months, though the geographical region where TOSV is expanding includes other countries in the Mediterranean basin. TOSV is transmitted to humans by the Phlebotomus species of sandflies. Though the animal reservoir has not been identified, TOSV has been isolated from the brain of a bat, which raises the question of it possibly being a host to the virus. TOSV causes aseptic meningitis in 95% of the people it infects, meningoencephalitis in 4.5% of those infected, and an influenza-like illness in the remaining .5% who are infected. Recently, unusual symptoms associated with TOSV have included ischemic complications and hydrocephalus. TOSV is emerging as an important pathogen as its distribution increases due to changes in the climate, globalization and habitat modification. Other than supportive therapy, there is no treatment for infection with TOSV. PMID: 20517492 Source: Regenstrief LOINC

Fully-Specified Name

Toscana virus Ab.IgG

Additional Names

Short Name
Display Name
Toscana virus IgG IA Ql (CSF)
Consumer Name Alpha Get Info
Toscana virus IgG antibody, Spinal fluid

Example Answer List: LL2010-8

Source: Estonian Society of Laboratory Medicine
Answer Code Score Answer ID
PositiveCopyright ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright ID:260385009 Negative (qualifier value) LA6577-6
Borderline LA4259-3

Basic Attributes

First Released
Version 2.52
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Toskana-Virus Ak.IgG:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Immunoassay
Synonyms: TOS; Sandmücken-Fieber; Toscana-Virus; Zerebrospinalflüssigkeit
es-ES Spanish (Spain) Virus Toscana IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:IA
es-MX Spanish (Mexico) Toscana virus Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunoensayo
fr-FR French (France) Toscana virus Ac IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunoanalyse
it-IT Italian (Italy) Virus Toscana Ab.IgG:PrThr:Pt:LCS:Ord:IA
Synonyms: anticorpi IgG anticorpo Immunoassay Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) Toscana virus As.IgG:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA
pl-PL Polish (Poland) Wirus gorączki wywołanej przez muchę piaskową typ toskański Ab.IgG:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:metoda immunologiczna
Synonyms: IgG Przeciwciała do toskańskiego typu wirusa gorączki wywołanej przez muchę piaskową Przeciwciała IgG do toskańskiego typu wirusa gorączki wywołanej przez muchę piaskową Toskański typ wirusa gorączki wywołanej przez muchę piaskową
tr-TR Turkish (Turkey) Toscana virüs Ab.IgG:MevcEşik:Zmlı:BOS:Srl:İA
Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) 托斯卡纳病毒 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Toscana 病毒 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液(Cerebral spinal fluid,CSF) 脑脊髓液

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