78202-9

9q34 chromosome region deletion [Presence] in Blood or Tissue by FISH

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Term Description

This term was created for, but is not limited in use to, the Vysis 9q34 SpectrumAqua FISH Probe Kit, which is intended to detect deletion of the 9q34 chromosome region.
Source: Regenstrief LOINC

Part Descriptions

LP189751-3   9q34 chromosome region
A deletion of chromosome region 9q34 is associated with chronic myelogenous leukemia (CML). Most patients with CML have the characteristic t(9;22) (q34;q11.2) translocation that results in fusion of the BCR and ABL1 genes. A small subset of CML cases have the 9q34 deletion, which is associated with poor prognosis in CML patients under treatment with interferon therapy. PMID: 19222642 Fluorescence in situ Hybridization (FISH) is used to detect deletion of the 9q34 region around the argininosuccinate synthetase (ASS) gene. Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component

9q34 chromosome region deletion

Property

PrThr

Time

Pt

System

Bld/Tiss

Scale

Ord

Method

FISH

Additional Names

Long Common Name

9q34 chromosome region deletion [Presence] in Blood or Tissue by FISH

Short Name

9q34 Del Bld/T Ql FISH

Display Name

9q34 chromosome region del FISH Ql (Bld/Tiss)

Consumer Name Alpha Get Info

9q34 chromosome region deletion analysis, Blood or tissue specimen

Example Answer List: LL744-4

Basic Attributes

Class

MOLPATH.DEL

Type

Laboratory

First Released

Version 2.54

Last Updated

Version 2.61

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Language Variants Get Info

Related Names

• ABL
• bcr/abl
• Blood
• Chromosom
• Chromosomes
• Chronic myeloid leukemia
• CML
• Cyto loc
• Del
• Deletions
• Fluorescent in situ hybridization
• Genetics
• Heredity
• Heritable
• Inherited
• Molecular pathology
• MOLPATH
• MOLPATH.DELETIONS
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Tissue
• Tissue, unspecified
• WB
• Whole blood
• Whole blood or Tissue

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78202-9

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.