Version 2.77

Part Descriptions

LP36229-0   CCND1 gene
The CCND1 gene (cyclin D1) [HGNC Gene ID:1582] is located on chromosome 11q13. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008] [NCBI Gene ID:595] Source: National Center for Biotechnology Information (NCBI) Gene

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
CCND1 gene duplication
Property
Imp
Time
Pt
System
Bld/Tiss
Scale
Nar
Method
FISH

Additional Names

Short Name
CCND1 gene Dp Bld/T FISH-Imp
Display Name
CCND1 gene dup FISH Nar (Bld/Tiss) [Interp]
Consumer Name Alpha Get Info
Interpretation of CCND1 gene duplication analysis test result, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.DELDUP
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.61
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gen CCND1 Duplicación:Impresión/interpretación del estudio:Punto temporal:Sangre o tejido:Narrativo:Hibridación in situ fluoresente (FISH)
es-MX Spanish (Mexico) Duplicación del gen CCND1:Impresión / interpretación del estudio:Punto temporal:Sangre o tejido:Narrativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) CCND1 gène duplication:Interprétation:Ponctuel:Sang/Tissu:Résultat textuel:FISH
it-IT Italian (Italy) CCND1, gene , duplicazione:Imp:Pt:Sangue/Tess:Nar:FISH
Synonyms: Delezione o duplicazione genica Gene CCND1 Ibridazione in situ fluorescente (FISH) Impressione/interpretazione di studio Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) CCND1-gen duplicatie:interpretatie:moment:bloed of weefsel:tekstueel:FISH
Synonyms: CCND1 gen
tr-TR Turkish (Turkey) CCND1 geni dublikasyon:İzlnm:Zmlı:Kan/Dk:Öykü:FISH
Synonyms: çiftleme
zh-CN Chinese (China) CCND1 基因 复制:印象:时间点:全血/组织:叙述型:FISH
Synonyms: B 细胞 CLL;B 细胞慢性淋巴细胞白血病;BCL1;BCL-1;D11S287E;HGNC:988;PRAD1;U21B31;慢性 B 淋巴细胞白血病;淋巴瘤 1;甲状旁腺腺上皮增生症 1;甲状旁腺腺瘤病 1;细胞周期素 D1;细胞周期蛋白 D1 Fluorescent in situ hybridization;荧光原位杂交 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 印象是一种诊断陈述,始终是对其他某种观察指标的解释或抽象(一系列检验项目结果、一幅图像或者整个某位病人),而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 基因复制;基因重复;重复 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78209-4