78359-7

Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate [Enzymatic activity ratio] in Fibroblast

Active

Term Description

Medium- and long-chain acyl CoA dehydrogenase deficiencies can be differentiated based on the ratio of palmitate oxidation LOINC 78358-9 and myristate oxidation LOINC 78360-5 in cultured fibroblasts. Patients with medium chain acyl-CoA dehydrogenase deficiency (MCAD) typically have a high palmitate/myristate (P/M) ratio. Long-chain defects, including VLCAD and LCHAD, generally have a low P/M ratio. PMID: 10709659

LOINC Names Get Info

Fully-Specified Name: Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate:CRto:Pt:Fibroblasts:Qn:
Long Common Name: Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate [Enzymatic activity ratio] in Fibroblast
Short Name: ACADs.palmitate/ACADs.myristate Fib-cRto
Display Name: Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate (Fibroblast) [Catalytic ratio]
Consumer Name Alpha Get Info: Acyl coA dehydrogenases.palmitate substrate/Acyl CoA Dehydrogenases.myristate Substrate, Fibroblast

Part Model Get Info

Component
Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate
LP284875-4
- Analyte
  Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate
  LP284875-4
  - Component Numerator
    Acyl CoA dehydrogenases.palmitate substrate
    LP199482-3
    - Component Numerator Core
      Acyl CoA dehydrogenases.palmitate substrate
      LP199482-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Acyl CoA dehydrogenases.myristate substrate
    LP199483-1
    - Component Denominator Core
      Acyl CoA dehydrogenases.myristate substrate
      LP199483-1
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
CRto
LP6791-0
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Fibroblasts
LP7234-0
- System Core
  Fibroblasts
  LP7234-0
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.54 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
74533-1	Fatty acid oxidation panel - Fibroblast

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Acyl-CoA-dehydrogenázy.substrát palmitát/acyl-CoA-dehydrogenázy.substrát myristát:Katalytický poměr:Časový bod:Fibroblast:Kvantitativní:
el-GR	Greek (Greece)	Ακυλο-CoA αφυδρογονάσες.παλμιτικό υπόστρωμα/Ακυλο-CoA αφυδρογονάσες.μυριστικό υπόστρωμα:CRto:Pt:Ινοβλάστες:Qn: Synonyms: CHEM CRto Pt Qn Ακυλο-CoA αφυδρογονάσες Ακυλο-CoA αφυδρογονάσες.μυριστικό υπόστρωμα Ακυλο-CoA αφυδρογονάσες.παλμιτικό υπόστρωμα Ινοβλάστες Μυριστικό Παλμιτικό
es-ES	Spanish (Spain)	Acil Coenzima A deshidrogenasas.sustrato palmitato/Acil Coenzima A deshidrogenasas.sustrato miristato:Relacion de concentración catalítica:Punto temporal:Fibroblastos:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Acil CoA deshidrogenasas, sustrato palmitato / acil CoA deshidrogenasas, sustrato miristato:Relación catalítica:Punto temporal:Fibroblasto:Cuantitativo:
fr-FR	French (France)	Acyl CoA déshydrogénases substrat palmitate/acyl CoA déshydrogénases substrat myristate:Catalytique ratio:Ponctuel:Fibroblastes:Numérique:
it-IT	Italian (Italy)	Acil Co deidrogenasi.substrato palmitato/Acil CoA deidrogenasi.subastrato miristato:CCrto:Pt:Fibroblasti:Qn: Synonyms: Chimica Fibroblasto Miristato (C14:0) Palmitato (C16:0) Punto nel tempo (episodio) Rapporto di Concentrazione Catalitica
nl-NL	Dutch (Netherlands)	acyl-CoA-dehydrogenase.palmitaatsubstraat/acyl-CoA-dehydrogenasen.myristaatsubstraat:enzymatische activiteit verhouding:moment:fibroblast:kwantitatief:
pl-PL	Polish (Poland)	Dehydrogenazy acylo-CoA.Substrat palmitynianowy/dehydrogenazy acylo-CoA, substrat murystynianu:współczynnik katalityczny:punkt w czasie:fibroblasty:ilościowy: Synonyms: Substrat palmitynianowy dla dehydrogenazy acylo-CoA
tr-TR	Turkish (Turkey)	Açil KoA dehidrojenazlar.palmitat substrat/Açil KoA dehidrojeazlar.miristat substrat:KtlKonsOr:Zmlı:Fibroblastlar:Kant:
zh-CN	Chinese (China)	酰基 CoA 脱氢酶.棕榈酸底物/酰基 CoA 脱氢酶.肉豆蔻酸底物:催化比率:时间点:成纤维细胞:定量型: Synonyms: AcdA;酰基辅酶 A 脱氢酶 C14:0;十四酸;十四酸, C14:0;肉豆蔻酸, C14:0 C16:0;十六烷酸;十六烷酸, C16:0;十六酸;十六酸, C16:0;棕榈酸, C16:0;软脂酸;软脂酸, C16:0 催化比;催化比值;催化浓度比;催化浓度比值;催化浓度比率化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间纤维原细胞;纤维母细胞酰基 CoA 脱氢酶（AcdA、酰基辅酶 A 脱氢酶）.棕榈酸（C16:0、十六烷酸、十六烷酸, C16:0、十六酸、十六酸, C16:0、棕榈酸, C16:0、软脂酸、软脂酸, C16:0）底物酰基 CoA 脱氢酶（AcdA、酰基辅酶 A 脱氢酶）.肉豆蔻酸（C14:0、十四酸、十四酸, C14:0、肉豆蔻酸, C14:0）底物

Example Units

Unit	Source
{ratio}	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78359-7

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.