78440-5
risperiDONE trough and 9-Hydroxyrisperidone panel - Serum or Plasma
Active
72656-2 risperiDONE [Mass/volume] in Serum or Plasma --trough
Part Descriptions
LP17872-0 risperiDONE
Risperidone (Belivon®, Rispen®, Risperdal®) is an atypical antipsychotic medication mostly used to treat delusional psychosis (e.g. schizophrenia). It is also used to treat some forms of bipolar disorder, psychotic depression, Tourette syndrome, and autistic spectrum disorders. Risperidone is a dopamine antagonist possessing antiserotonergic, antiadrenergic and antihistaminergic properties. Side effects of risperidone include significant weight gain and metabolic problems, as well as tardive dyskinesia and neuroleptic malignant syndrome. Risperidone and other antipsychotics also increase the risk of death in patients with dementia. The major active metabolite of Risperidone is 9-hydroxyrisperidone, which has similar pharmacodynamics to risperidone and remains in the body for much longer. It has also been developed as an antipsychotic and is known as paliperidone.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Risperidone
LP17872-0 risperiDONE
A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
Source: National Library of Medicine, MeSH 2006
LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Trough levels for therapeutic drug monitoring
Fully-Specified Name
- Component
- risperiDONE^trough
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- risperiDONE Trough SerPl-mCnc
- Display Name
- risperiDONE trough [Mass/Vol]
- Consumer Name Alpha Get Info
- risperiDONE trough, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.42
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
78440-5 | risperiDONE trough and 9-Hydroxyrisperidone panel - Serum or Plasma |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Risperidona^Valle monitorización terapéutica de fármacos: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | risperiDONE ^ comedero: |
et-EE | Estonian (Estonia) | Risperidoon^baas: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-BE | French (Belgium) | Rispéridone^Creux: Synonyms: Minimum, nadir |
fr-FR | French (France) | Rispéridone taux résiduel: |
fr-CA | French (Canada) | Rispéridone^Creux: Synonyms: #REF! |
it-IT | Italian (Italy) | Risperidone^valore minimo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM |
nl-NL | Dutch (Netherlands) | risperidon^dalspiegel: |
pt-BR | Portuguese (Brazil) | Risperidona^basal: |
ru-RU | Russian (Russian Federation) | Рисперидон^остаточная концентрация: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Risperidon^en düşük: Synonyms: çukur düzey |
zh-CN | Chinese (China) | 利培酮^波谷: Synonyms: 一剂药物的初始剂量; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
9383-1 9-Hydroxyrisperidone [Mass/volume] in Serum or Plasma
Term Description
risperidone metabolite
Source: Regenstrief LOINC
Part Descriptions
LP17865-4 9-Hydroxyrisperidone
9-Hydroxyrisperidone, also called paliperidone, is an active metabolite of risperidone and is itself a prescribable atypical antipsychotic. Although 9-Hydroxyrisperidone is a metabolite of risperidone, they have several important differences including serotonin 5-HT2A and dopamine D2 receptor binding, and ability to cross the blood brain barrier (BBB). Risperidone has a significantly lower 5-HT2A/D2 binding ratio and crosses the BBB more effectively. Both drugs are used to treat schizophrenia and other related disorders. PMID: 25943458
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 9-Hydroxyrisperidone
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- 9OH-risperidone SerPl-mCnc
- Display Name
- 9-Hydroxyrisperidone [Mass/Vol]
- Consumer Name Alpha Get Info
- 9-Hydroxyrisperidone, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0i
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 7496
Member of these Panels
LOINC | Long Common Name |
---|---|
55157-2 | risperiDONE and 9-Hydroxyrisperidone panel - Serum or Plasma |
78440-5 | risperiDONE trough and 9-Hydroxyrisperidone panel - Serum or Plasma |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG24966-0 | 9-Hydroxyrisperidone| |
LG42268-9 | 9-Hydroxyrisperidone| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | 9-Hydroxyrisperidon: Synonyms: 9-OH-Risperidon |
de-AT | German (Austria) | Synonyms: 9-OH-Risperidon |
es-MX | Spanish (Mexico) | 9-hidroxirisperidona: |
es-ES | Spanish (Spain) | 9-Hidroxirisperidona: Synonyms: Cuantitativo |
es-AR | Spanish (Argentina) | 9-hidroxirisperidona: |
et-EE | Estonian (Estonia) | 9-hüdroksürisperidoon: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | 9-hydroxyrispéridone: |
fr-BE | French (Belgium) | 9-hydroxyrispéridone: |
fr-FR | French (France) | 9-hydroxyrispéridone: |
it-IT | Italian (Italy) | 9-Idrossirisperidone: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 9-하이드록시리스페리돈: |
nl-NL | Dutch (Netherlands) | 9-hydroxyrisperidon: |
pt-BR | Portuguese (Brazil) | 9-Hidroxirisperidona: Synonyms: ; |
ru-RU | Russian (Russian Federation) | 9-Гидроксирисперидон: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | 9-Hidroksirisperidon: |
zh-CN | Chinese (China) | 9-羟基利培酮: Synonyms: 利培酮代谢物; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
ng/mL | REGENSTRIEF |