Version 2.78

72656-2 risperiDONE [Mass/volume] in Serum or Plasma --trough

Part Descriptions

LP17872-0   risperiDONE
Risperidone (Belivon®, Rispen®, Risperdal®) is an atypical antipsychotic medication mostly used to treat delusional psychosis (e.g. schizophrenia). It is also used to treat some forms of bipolar disorder, psychotic depression, Tourette syndrome, and autistic spectrum disorders. Risperidone is a dopamine antagonist possessing antiserotonergic, antiadrenergic and antihistaminergic properties. Side effects of risperidone include significant weight gain and metabolic problems, as well as tardive dyskinesia and neuroleptic malignant syndrome. Risperidone and other antipsychotics also increase the risk of death in patients with dementia. The major active metabolite of Risperidone is 9-hydroxyrisperidone, which has similar pharmacodynamics to risperidone and remains in the body for much longer. It has also been developed as an antipsychotic and is known as paliperidone. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Risperidone

LP17872-0   risperiDONE
A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA. Source: National Library of Medicine, MeSH 2006

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
risperiDONE^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
risperiDONE Trough SerPl-mCnc
Display Name
risperiDONE trough [Mass/Vol]
Consumer Name Alpha Get Info
risperiDONE trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
78440-5 risperiDONE trough and 9-Hydroxyrisperidone panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Risperidona^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) risperiDONE ^ comedero:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Risperidoon^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-BE French (Belgium) Rispéridone^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
fr-FR French (France) Rispéridone taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-CA French (Canada) Rispéridone^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: #REF!
it-IT Italian (Italy) Risperidone^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL Dutch (Netherlands) risperidon^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Risperidona^basal::Pt:Soro/Plas:Qn:
ru-RU Russian (Russian Federation) Рисперидон^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Risperidon^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CN Chinese (China) 利培酮^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 维思通;瑞斯哌东;瑞司哌酮;3-[2-[4-(6-氟-1,2-苯并异噁唑-3-基)-1-哌啶基]乙基]-6,7,8,9-四氢-2-甲基-4H-吡啶并[1,2-α]嘧啶-4-酮;risperidone;3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-α]pyrimidin-4-one;Risperidone intermediates;Risperi 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
mg/L Example UCUM Units

9383-1 9-Hydroxyrisperidone [Mass/volume] in Serum or Plasma

Term Description

risperidone metabolite
Source: Regenstrief LOINC

Part Descriptions

LP17865-4   9-Hydroxyrisperidone
9-Hydroxyrisperidone, also called paliperidone, is an active metabolite of risperidone and is itself a prescribable atypical antipsychotic. Although 9-Hydroxyrisperidone is a metabolite of risperidone, they have several important differences including serotonin 5-HT2A and dopamine D2 receptor binding, and ability to cross the blood brain barrier (BBB). Risperidone has a significantly lower 5-HT2A/D2 binding ratio and crosses the BBB more effectively. Both drugs are used to treat schizophrenia and other related disorders. PMID: 25943458 Source: Regenstrief LOINC

Fully-Specified Name

Component
9-Hydroxyrisperidone
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
9OH-risperidone SerPl-mCnc
Display Name
9-Hydroxyrisperidone [Mass/Vol]
Consumer Name Alpha Get Info
9-Hydroxyrisperidone, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0i
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
7496

Member of these Panels

LOINC Long Common Name
55157-2 risperiDONE and 9-Hydroxyrisperidone panel - Serum or Plasma
78440-5 risperiDONE trough and 9-Hydroxyrisperidone panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG24966-0 9-Hydroxyrisperidone|MCnc|Pt|ANYBldSerPl
LG42268-9 9-Hydroxyrisperidone|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) 9-Hydroxyrisperidon:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
Synonyms: 9-OH-Risperidon
de-AT German (Austria) Synonyms: 9-OH-Risperidon
es-MX Spanish (Mexico) 9-hidroxirisperidona:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) 9-Hidroxirisperidona:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-AR Spanish (Argentina) 9-hidroxirisperidona:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
et-EE Estonian (Estonia) 9-hüdroksürisperidoon:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) 9-hydroxyrispéridone:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-BE French (Belgium) 9-hydroxyrispéridone:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) 9-hydroxyrispéridone:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) 9-Idrossirisperidone:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 9-하이드록시리스페리돈:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) 9-hydroxyrisperidon:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) 9-Hidroxirisperidona:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; 9OH-Risperidone; Risperidone metAcolite; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) 9-Гидроксирисперидон:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) 9-Hidroksirisperidon:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 9-羟基利培酮:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 利培酮代谢物;利培酮代谢产物;9-羟利培酮;帕潘立酮;6,7,8,9-四氢-3-(2-(4-(6-氟-1,2-苯并异恶唑-3-基)-1-哌啶基)乙基)-9-羟基-2-甲基-4H-吡啶并[2,1-a]嘧啶-4-酮;Paliperidone;INVEGA;INVEGA Sustenna;9-Hydroxyrisperidone;6,7,8,9-Tetrahydro-3-(2-(4-(6-fluro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-9-hydroxy-2- 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
ng/mL Example UCUM Units
ng/mL REGENSTRIEF