Version 2.78

Term Description

This term was created for, but not limited in use to, the submitter's Roche cobas CMV IgG Antibody Avidity to Cytomegalovius test kit.
Source: Regenstrief LOINC

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ab.IgG avidity
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
IA

Additional Names

Long Common Name
Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
Short Name
CMV IgG Avidity SerPl Ql IA
Display Name
CMV IgG avidity IA Ql
Consumer Name Alpha Get Info
Cytomegalovirus (CMV) IgG avidity, Blood

Example Answer List: LL3257-4

Source: Roche Diagnostics International
Answer Code Score Answer ID
High avidity LA22673-0
Gray-zone LA22672-2
Low avidity LA22671-4

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus Ak.IgG-Avidität:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:Immunoassay
Synonyms: CMV
es-ES Spanish (Spain) Citomegalovirus Avidez IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-MX Spanish (Mexico) Citomegalovirus Ab.IgG avidez:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
et-EE Estonian (Estonia) Tsütomegaloviirus antikehad.IgG aviidsus:PrThr:Pt:S/P:Ord:IA
Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA French (Canada) Cytomégalovirus, Ac.avidité des IgG:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:IA
fr-FR French (France) Cytomégalovirus Ac IgG avidité:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
fr-BE French (Belgium) Cytomégalovirus Anticorps.avidité des IgG:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:IA
Synonyms: Anticorps CMV
it-IT Italian (Italy) Citomegalovirus Ab.avidità IgG:PrThr:Pt:Siero/Plasma:Ord:IA
Synonyms: anticorpi IgG anticorpo Avidità delle IgG; test avidità delle IgG Immunoassay Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) Cytomegalovirus As.IgG-aviditeit:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA IgG Bindingskracht
pl-PL Polish (Poland) Wirus cytomegalii Ab.IgG awidność:granica wykrywalności:punkt w czasie:surowica lub osocze:półilościowy:metoda immunologiczna
Synonyms: Awdiność przecwciał do cytomegalowirusa w klasie IgG Cytomegalowirus IgG Przecwciała do cytomegalowirusa Przecwciała IgG do cytomegalowirusa
ru-RU Russian (Russian Federation) Цитомегаловирус Ат.IgG авидность:PrThr:ТчкВрм:Сыв/Плаз:Пор:IA
Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus Ab.IgG avidite:MevcEşik:Zmlı:Ser/Plaz:Srl:İA
Synonyms: Ak Ak.IgG Ak.IgG avidite İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) 巨细胞病毒 抗体.IgG 亲合力:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法
Synonyms: Ab.IgG 亲合力;IgG 亲合力;抗体 IgG 亲合力 Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CMV Ab CMV Ab.IgG CMV Ab.IgG 亲合力 CMV IgG CMV IgG 亲合力 CMV 抗体 CMV 抗体.IgG CMV 抗体.IgG 亲合力 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 巨细胞病毒 Ab 巨细胞病毒 Ab.IgG 巨细胞病毒 Ab.IgG 亲合力 巨细胞病毒 IgG 巨细胞病毒 IgG 亲合力 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 血清或血浆

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