78445-4

Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

Active

Term Description

This term was created for, but not limited in use to, the submitter's Roche cobas CMV IgG Antibody Avidity to Cytomegalovius test kit.

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name

Cytomegalovirus Ab.IgG avidity:PrThr:Pt:Ser/Plas:Ord:IA

Long Common Name

Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

Short Name

CMV IgG Avidity SerPl Ql IA

Display Name

CMV IgG avidity IA Ql

Consumer Name Alpha Get Info

Cytomegalovirus (CMV) IgG avidity, Blood

Part Model Get Info

• Component

  Cytomegalovirus Ab.IgG avidity
  LP40408-4

  • Analyte

    Cytomegalovirus Ab.IgG avidity
    LP40408-4

    • Component Numerator

      Cytomegalovirus Ab.IgG avidity
      LP40408-4

      • Component Numerator Core

        Cytomegalovirus
        LP14255-1

      • Component Numerator Core Suffix

        Ab.IgG avidity
        LP32413-4

    • Component Denominator

      NULL
       

      • Component Denominator Core

        NULL
         

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  PrThr
  LP217195-9

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  Ser/Plas
  LP7576-4

  • System Core

    Ser/Plas
    LP7576-4

  • Super System

    NULL
     

• Scale

  Ord
  LP7751-3

• Method

  IA
  LP217197-5

Example Answer List: LL3257-4

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.54

Last Updated

Version 2.56 (MIN)

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Member of these Panels

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Autoantibodies
• Autoantibody
• CMV
• Cytomegalo virus
• Cytomgal
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• HHV-5
• Human Herpesvirus-5
• IAA
• ID
• Immune globulin G
• Immunoglobulin G
• Infectious Disease
• InfectiousDisease
• MEIA
• Microbiology
• Ordinal
• Pl
• Plasma
• Plsm
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• SerP
• SerPl
• SerPlas
• Serum
• Serum or plasma
• SR
• SUDS

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78445-4

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.