78771-3
9-Hydroxyrisperidone [Mass/mass] in Hair
Active
Term Description
In general hair analysis provides a longer surveillance window for drug use than other methods because hair retains drugs longer (weeks or months, compared with days detectable in blood or urine). Collecting hair specimens is also less invasive than urine or blood sampling and provides a simple and fast method for detection and quantification of Risperidone (RSP) and its major metabolite, 9-hydroxyrisperidone (9-OH-RSP). One study suggests a better relationship between the administered dose and hair concentration for 9-OH-RSP, than for the parent drug. PMID: 19595645 Drawbacks for hair analysis include expense, and environmental contamination of the specimen.
Source: Regenstrief LOINC
Part Description
LP17865-4 9-Hydroxyrisperidone
9-Hydroxyrisperidone, also called paliperidone, is an active metabolite of risperidone and is itself a prescribable atypical antipsychotic. Although 9-Hydroxyrisperidone is a metabolite of risperidone, they have several important differences including serotonin 5-HT2A and dopamine D2 receptor binding, and ability to cross the blood brain barrier (BBB). Risperidone has a significantly lower 5-HT2A/D2 binding ratio and crosses the BBB more effectively. Both drugs are used to treat schizophrenia and other related disorders. PMID: 25943458
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 9-Hydroxyrisperidone
- Property
- MCnt
- Time
- Pt
- System
- Hair
- Scale
- Qn
- Method
Additional Names
- Short Name
- 9OH-risperidone Hair-mCnt
- Display Name
- 9-Hydroxyrisperidone (Hair) [Mass/Mass]
- Consumer Name Alpha Get Info
- 9-Hydroxyrisperidone, Hair
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | 9-Hidroxirisperidona: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 9-hidroxirisperidona: |
et-EE | Estonian (Estonia) | 9-hüdroksürisperidoon: Synonyms: Juhuslik Juuksed Kvantitatiivne |
fr-CA | French (Canada) | 9-hydroxyrispéridone: |
fr-FR | French (France) | 9-hydroxyrispéridone: |
fr-BE | French (Belgium) | 9-hydroxyrispéridone: |
it-IT | Italian (Italy) | 9-Idrossirisperidone: Synonyms: Contenuto di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | 9-hydroxyrisperidon: |
ru-RU | Russian (Russian Federation) | 9-Гидроксирисперидон: Synonyms: Количественный Масса содержание Точка во времени; |
tr-TR | Turkish (Turkey) | 9-Hidroksirisperidon: |
zh-CN | Chinese (China) | 9-羟基利培酮: Synonyms: 利培酮代谢物; |
Example Units
Unit | Source |
---|---|
pg/mg | Example UCUM Units |
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