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Term Description

This term is used to report the risk score for moderate to severe (grade 3A or higher) acute cellular transplant rejection in heart transplant recipients with stable allograft function. The test assesses the expression of 11 genes (ITGAM, FLT3, IL1R2, G6B, PF4, WDR40A, MIR, ARHU, PDCD1, ITGA4 AND SEMA7A) using PCR with RNA isolated from peripheral blood mononuclear cells, and the gene expression data is then used to calculate a score that ranges from 0-40, with a lower score indicating a lower risk for rejection. In the Cardiac Allograft Rejection Gene Expression Observational (CARGO) study, patients who were at least 12 months post-transplant and who had a score less than 30 were very unlikely to have grade 3A acute cellular rejection at the time of testing (negative predictive value 99.6%). PMID: 16433769 This term was created for XDx Reference Laboratory's AlloMap test, which is indicated for heart transplant patients who are at least 15 years of age and 55 or more days post-transplant.

LOINC Names Get Info

Fully-Specified Name
Heart transplant acute cellular rejection risk:Score:Pt:Bld MC:Qn:Calculated.AlloMap
Long Common Name
Heart transplant acute cellular rejection risk [Score] in Mononuclear cells Calculated by AlloMap
Short Name
Heart tx acute reject Score MC AlloMap
Display Name
Heart transplant acute cellular rejection risk Calculated by AlloMap (Bld MC) [Score]
Consumer Name Alpha Get Info
Heart transplant acute cellular rejection risk, Blood

Part Model Get Info

  • Component
    Heart transplant acute cellular rejection risk
    LP200197-4
    • Analyte
      Heart transplant acute cellular rejection risk
      LP200197-4
      • Component Numerator
        Heart transplant acute cellular rejection risk
        LP200197-4
        • Component Numerator Core
          Heart transplant acute cellular rejection risk
          LP200197-4
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Score
    LP185820-0
  • Time
    Pt
    LP6960-1
  • System
    Bld MC
    LP193850-7
  • Scale
    Qn
    LP7753-9
  • Method
    Calculated.AlloMap
    LP200198-2

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
8516

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Transplantace srdce riziko akutní buněčné rejekce:Skóre:Časový bod:Buňky krevní mononukleární:Kvantitativní:Vypočteno pomocí AlloMap
el-GRGreek (Greece)Κίνδυνος οξείας κυτταρικής απόρριψης κατά τη μεταμόσχευση καρδιάς:Βαθμολογία:Pt:Αίμα Μονοπύρηνα κύτταρα:Qn:Υπολογιζόμενη.AlloMap
Synonyms: MOLPATH Pt Qn Αίμα Αίμα Μονοπύρηνα κύτταρα Βαθμολογία Κίνδυνος οξείας κυτταρικής απόρριψης κατά τη μεταμόσχευση καρδιάς Υπολογιζόμενη.AlloMap Υπολογιζόμενο
es-ESSpanish (Spain)riesgo de rechazo celular agudo en el trasplante de corazón:Puntuación:Punto temporal:Celulas Mononucleares sanguíneas:Qn:Calculado por AlloMap
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Riesgo de rechazo celular agudo del trasplante de corazón:Puntaje:Punto temporal:Células mononucleares de sangre:Cuantitativo:Calculado por AlloMap
fr-FRFrench (France)Risque de rejet cellulaire aigu d'une greffe cardiaque:Score:Ponctuel:Cellules mononucléées de sang périphérique:Numérique:Calculé par AlloMap
it-ITItalian (Italy)Alto rischio di rigetto cellulare acuto del trapianto del cuore:Punteggio:Pt:Cellule mononucleate da sangue intero:Qn:Calcolato.AlloMap
Synonyms: Calcolato mediante AlloMap Patologia molecolare Punto nel tempo (episodio) Sangue
pl-PLPolish (Poland)Przeszczep serca ryzyko ostrego odrzucenia komórkowego:liczba punktów:punkt w czasie:jednojądrzaste komórki krwi:ilościowy:wyliczony przy pomocy AlloMap
Synonyms: Ryzyko ostrego odrzucenia komórkowego przeszczepu serca
zh-CNChinese (China)心脏移植急性细胞排斥风险:评分:时间点:全血单个核细胞:定量型:计算法.AlloMap
Synonyms: 全血（血液、血）单个核细胞（单核细胞、MC）;全血标本（样品、样本、试样）单个核细胞 分值;得分;分数 分子病理学;分子病理学试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 心脏移植（心脏移植术、换心手术、心脏移植物）急性细胞排斥（急性细胞排斥反应）风险（危险、风险率、风险性、危险率、危险性） 时刻;随机;随意;瞬间 血;血液 计算;计算型方法

Example Units

UnitSource
{score}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79102-0