Version 2.80

Part Description

LP200416-8   t(2;3)(q13;p25)(PAX8,PPARG)
The PAX8/PPARG (paired box 8/peroxisome proliferator-activated receptor gamma) gene rearrangement is created by a translocation between chromosome arms 2q and 3p where the entire coding region of the PPARG transcription factor gene is fused with the first 8 to 10 exons of the PAX8 gene. PMID: 10958784 Translocations of the PAX8/PPARG genes play a role in the pathogenesis of some follicular thyroid carcinomas and follicular-variant papillary thyroid carcinoma. PMID: 20056739 Several testing methods are used to detect the rearrangement, including fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and reverse-transcription PCR (RT-PCR). Source: Regenstrief LOINC

Fully-Specified Name

Component
t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Molgen

Additional Names

Long Common Name
t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript [Presence] in Tissue by Molecular genetics method
Short Name
t(2;3)(PAX8,PPARG) Tiss Ql
Display Name
t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript Molgen Ql (Tiss)
Consumer Name Alpha Get Info
t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript analysis, Tissue

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) t(2;3)(q13;p25)(PAX8,PPARG) μεταγραφή συγχώνευσης:PrThr:Pt:Ιστός:Ord:Μοριακή γενετική
Synonyms: PAX8 PrThr t(2;3)(q13;p25)(PAX8,PPARG)
es-ES Spanish (Spain) t(2;3)(q13;p25)(PAX8,PPARG) Tránscritos de fusión:PrThr:Punto temporal:Tejido:Ord:Genética molecular
es-MX Spanish (Mexico) t (2; 3) (q13; p25) (PAX8, PPARG) transcripción de fusión:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Genética molecular
fr-FR French (France) t(2;3)(q13;p25)(PAX8,PPARG) transcrit de fusion:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Biologie moléculaire
fr-CA French (Canada) t(2;3)(q13;p25)(PAX8,PPARG) transcrit de fusion:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Molgen
it-IT Italian (Italy) t(2;3)(q13;p25)(PAX8,PPARG), trascritto di fusione:PrThr:Pt:Tessuto:Ord:Molgen
Synonyms: Genetica molecolare Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(2;3)(q13;p25)(PAX8,PPARG) fusietranscript:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:moleculair genetisch onderzoek
Synonyms: molgen
tr-TR Turkish (Turkey) t(2;3)(q13;p25)(PAX8,PPARG) füzyon transkript:MevcEşik:Zmlı:Doku:Srl:Molgen
Synonyms: Mevcut
zh-CN Chinese (China) t(2;3)(q13;p25)(PAX8,PPARG) 融合转录物:存在情况或阈值:时间点:组织与涂片:序数型:分子遗传学类实验室方法
Synonyms: Ⅱ Ⅲ II III PAX-8;XPax8;配对盒基因 8;Paired box gene 8;转录因子配对盒家族成员;转录因子 PAX 家族成员;member of the paired box (PAX) family of transcription factors;PAX8 核蛋白;PAX8 核内蛋白;PAX8 nuclear protein 三 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 易位(2;3)(q13;p25)(PAX8,PPARG) 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79209-3