79209-3

t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript [Presence] in Tissue by Molecular genetics method

Active

Part Description

LP200416-8 t(2;3)(q13;p25)(PAX8,PPARG)
The PAX8/PPARG (paired box 8/peroxisome proliferator-activated receptor gamma) gene rearrangement is created by a translocation between chromosome arms 2q and 3p where the entire coding region of the PPARG transcription factor gene is fused with the first 8 to 10 exons of the PAX8 gene. PMID: 10958784 Translocations of the PAX8/PPARG genes play a role in the pathogenesis of some follicular thyroid carcinomas and follicular-variant papillary thyroid carcinoma. PMID: 20056739 Several testing methods are used to detect the rearrangement, including fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and reverse-transcription PCR (RT-PCR). Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript:PrThr:Pt:Tiss:Ord:Molgen
Long Common Name: t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript [Presence] in Tissue by Molecular genetics method
Short Name: t(2;3)(PAX8,PPARG) Tiss Ql
Display Name: t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript Molgen Ql (Tiss)
Consumer Name Alpha Get Info: t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript analysis, Tissue

Part Model Get Info

Component
t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript
LP229749-9
- Analyte
  t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript
  LP229749-9
  - Component Numerator
    t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript
    LP229749-9
    - Component Numerator Core
      t(2;3)(q13;p25)(PAX8,PPARG)
      LP200416-8
    - Component Numerator Core Suffix
      fusion transcript
      LP150217-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Tiss
LP7641-6
- System Core
  Tiss
  LP7641-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Molgen
LP6404-0

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MOLPATH.TRNLOC
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.56 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Fúzní transkript t(2;3)(q13;p25)(PAX8,PPARG):Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Molekulární genetika
el-GR	Greek (Greece)	t(2;3)(q13;p25)(PAX8,PPARG) μεταγραφή συγχώνευσης:PrThr:Pt:Ιστός:Ord:Μοριακή γενετική Synonyms: MOLPATH MOLPATH.TRNLOC Ord PAX8 PrThr Pt t(2;3)(q13;p25)(PAX8,PPARG) Ιστός μεταγραφή συγχώνευσης Μοριακή γενετική
es-ES	Spanish (Spain)	t(2;3)(q13;p25)(PAX8,PPARG) Tránscritos de fusión:PrThr:Punto temporal:Tejido:Ord:Genética molecular
es-MX	Spanish (Mexico)	t (2; 3) (q13; p25) (PAX8, PPARG) transcripción de fusión:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Genética molecular
fr-FR	French (France)	t(2;3)(q13;p25)(PAX8,PPARG) transcript de fusion:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Biologie moléculaire
fr-CA	French (Canada)	t(2;3)(q13;p25)(PAX8,PPARG) transcrit de fusion:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Molgen
it-IT	Italian (Italy)	t(2,3)(q13,p25)(PAX8,PPARG), trascritto di fusione:PrThr:Pt:Tessuto:Ord:Molgen Synonyms: Genetica molecolare Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci Traslocazione genetica
nl-NL	Dutch (Netherlands)	t(2;3)(q13;p25)(PAX8,PPARG) fusietranscript:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:moleculair genetisch onderzoek Synonyms: molgen
pl-PL	Polish (Poland)	T(2;3)(q13;p25)(PAX8,PPARG) transkrypt fuzyjny:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:genetyka molekularna Synonyms: diagnostyka molekularna Translokacja (2;3)(q13;p25)(PAX8,PPARG)
tr-TR	Turkish (Turkey)	t(2;3)(q13;p25)(PAX8,PPARG) füzyon transkript:MevcEşik:Zmlı:Doku:Srl:Molgen Synonyms: Mevcut
zh-CN	Chinese (China)	t(2;3)(q13;p25)(PAX8,PPARG) 融合转录物:存在情况或阈值:时间点:组织与涂片:序数型:分子遗传学类实验室方法 Synonyms: Ⅱ Ⅲ II III PAX-8;XPax8;配对盒基因 8;Paired box gene 8;转录因子配对盒家族成员;转录因子 PAX 家族成员;member of the paired box (PAX) family of transcription factors;PAX8 核蛋白;PAX8 核内蛋白;PAX8 nuclear protein 三依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应叁存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间易位(2;3)(q13;p25)(PAX8,PPARG) 未作说明的组织;组织;组织 & 涂片融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.