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Part Description

LP200417-6   Hepatocyte growth factor
Hepatocyte growth factor (HGF) is secreted by mesenchymal cells and acts as a cytokine, mainly on cells of epithelial origin, to regulate cell growth, motility, and morphogenesis. It plays a key role in angiogenesis, tumorogenesis, and tissue regeneration. HGF is secreted as an inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active molecule that binds to the c-Met receptor and activates a tyrosine kinase signaling cascade. Mutations in the HGF gene are associated with autosomal recessive deafness-39, a non-syndromic hearing loss. [NCBI Gene ID: 3082] HGF plasmid DNA therapy targeted to cardiomyocytes is being examined as a potential treatment for coronary artery disease and for damaged cardiac tissue post-myocardial infarction. HGF levels may also be a marker for prognosis in Chikungunya virus-induced arthralgia, where higher HGF levels correlate with higher rates of recovery. On the other hand, HGF has also been implicated in a variety of cancers, including of lung, pancreas, thyroid, colon, and breast. Source: Regenstrief LOINC, NCBI Gene ID: 3082

LOINC Names Get Info

Fully-Specified Name
Hepatocyte growth factor:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Hepatocyte growth factor [Mass/volume] in Serum or Plasma
Short Name
HGF SerPl-mCnc
Display Name
Hepatocyte growth factor [Mass/Vol]
Consumer Name Alpha Get Info
Hepatocyte growth factor, Blood

Part Model Get Info

  • Component
    Hepatocyte growth factor
    LP200417-6
    • Analyte
      Hepatocyte growth factor
      LP200417-6
      • Component Numerator
        Hepatocyte growth factor
        LP200417-6
        • Component Numerator Core
          Hepatocyte growth factor
          LP200417-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Růstový faktor hepatocytů:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Ηπατοκυτταρικός αυξητικός παράγοντας:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: CHEM MCnc Pt Qn Ηπατοκυτταρικός αυξητικός παράγοντας Ηπατοκύτταρο Ορός Ορός/Πλάσμα Πλάσμα
es-ESSpanish (Spain)Factor de crecimiento de hepatocitos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Factor de crecimiento de hepatocitos:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FRFrench (France)Hepatocyte growth factor:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)Epatocita, fattore di crescita:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Fattore id crescita degli epatociti Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NLDutch (Netherlands)hepatocyt groeifactor:massa/volume:moment:serum of plasma:kwantitatief:
pl-PLPolish (Poland)Czynnik wzrostu hepatocytów:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:
tr-TRTurkish (Turkey)Hepatost büyüme faktörü:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CNChinese (China)肝细胞生长因子:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 因素 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 系数 肝实质细胞 肝细胞生长素;Hepatocyte growth factor;HGF 血清或血浆

Example Units

UnitSource
pg/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79394-3