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Part Description

LP19492-5   Thiopurine methyltransferase
Thiopurine methyltransferase (TPMT) is an enzyme that catalyzes the S-methylation of thiopurine drugs including 6-mercatptopurine, thioguanine, and azathioprine (AZA). These drugs are used to treat acute lymphoblastic leukemia, inflammatory bowel disease, rheumatoid arthritis, and organ transplant rejection. Patients with low or absent TPMT activity are at increased risk for toxicity due to increased accumulation of unmetabolised drug. Information from Current Clinical Pharmacology. 2006;1:119-128. Source: Regenstrief Institute

LOINC Names Get Info

Fully-Specified Name
Thiopurine methyltransferase:CSub:Pt:RBC:Qn:
Long Common Name
Thiopurine methyltransferase [Enzymatic activity/substance] in Red Blood Cells
Short Name
TPMT cSub RBC
Display Name
Thiopurine methyltransferase (RBC) [Catalytic activity/Moles]
Consumer Name Alpha Get Info
Thiopurine methyltransferase, Red blood cells

Part Model Get Info

  • Component
    Thiopurine methyltransferase
    LP19492-5
    • Analyte
      Thiopurine methyltransferase
      LP19492-5
      • Component Numerator
        Thiopurine methyltransferase
        LP19492-5
        • Component Numerator Core
          Thiopurine methyltransferase
          LP19492-5
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CSub
    LP149700-9
  • Time
    Pt
    LP6960-1
  • System
    RBC
    LP7536-8
    • System Core
      RBC
      LP7536-8
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Thiopurinmethyltransferáza:Poměr katalytická aktivita/látkové množství:Časový bod:Erytrocyty:Kvantitativní:
el-GRGreek (Greece)Μεθυλοτρανσφεράση θειοπουρίνης:CSub:Pt:Ερυθρά αιμοσφαίρια:Qn:
Synonyms: CHEM CSub Pt Qn Ερυθρά αιμοσφαίρια Μεθυλοτρανσφεράση θειοπουρίνης
es-ESSpanish (Spain)Tiopurina metiltransferasa:CSub:Punto temporal:Glóbulos rojos:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Tiopurina metiltransferasa:Sustancia catalítica:Punto temporal:Eritrocitos:Cuantitativo:
fr-FRFrench (France)Thiopurine méthyltransférase:Substance catalytique:Ponctuel:Érythrocytes:Numérique:
it-ITItalian (Italy)Tiopurina metiltransferasi:CSub:Pt:RBC:Qn:
Synonyms: Chimica Globuli rossi Punto nel tempo (episodio) Sostanza catalitica
nl-NLDutch (Netherlands)thiopurinemethyltransferase:enzymatische activiteit/mol:moment:erytrocyten:kwantitatief:
Synonyms: rode bloedcellen
ru-RURussian (Russian Federation)Тиопурин метилтрансфераза:КаталВещ:ТчкВрм:Эритроциты:Колич:
Synonyms: Каталитическое вещество;Катализатор Количественный Тиопурин-S-метилтрансфераза Точка во времени;Момент
tr-TRTurkish (Turkey)Tiyopürin metiltransferaz:KtlSub:Zmlı:Eritrosit:Kant:
Synonyms: RBC
zh-CNChinese (China)硫嘌呤甲基转移酶:单位物质的量相对型催化活性:时间点:红细胞:定量型:
Synonyms: Catalytic substance;Csub;酶相对浓度;单位摩尔相对型催化活性;单位克分子相对型催化活性;催化性物质;催化性化学物质 RBC;RBCS;红血球;红血细胞;赤血球 TPMT;巯嘌呤甲基转移酶 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 转甲基酶

Example Units

UnitSource
umol/h/mmol{Hb}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79468-5