79594-8
Glycylproline/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP201675-8 Glycylproline
Glycylproline is an end product of collagen metabolism that is further cleaved by prolidase (EC 3.4.13.9); the resulting proline molecules are recycled into collagen or other proteins. Prolidase deficiency is a rare autosomal recessive disease characterized by chronic ulcerative dermatitis, mental retardation, frequent infections and massive urinary excretion of iminodipeptides. The disease has been confirmed to be due to hereditary prolidase deficiency. It has been reported that the activity of the enzyme against glycylproline (Gly-Pro) is almost totally deficient in patients with prolidase deficiency, whereas the activity against other substrates is not so deficient. Some patients with prolidase deficiency have a marked urinary excretion of the iminodipeptide Glycylproline. The urine from patients with pressure sores contains significantly more Glycylproline than the urine from the control. PMID: 16009141 PMID: 7629169 PMID: 1536787 PMID: 10582130
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
Creatinine
LOINC Names Get Info
- Fully-Specified Name
- Glycylproline/Creatinine:
SRto: Pt: Urine: Qn: - Long Common Name
- Glycylproline/Creatinine [Molar ratio] in Urine
- Short Name
- Gly-pro/Creat Ur-sRto
- Display Name
- Glycylproline/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- Glycylproline/Creatinine, Urine
Part Model Get Info
- Component
- Glycylproline/Creatinine
LP286120-3
- Analyte
- Glycylproline/Creatinine
LP286120-3
- Component Numerator
- Glycylproline
LP201675-8
- Component Numerator Core
- Glycylproline
LP201675-8
- Component Numerator Core Suffix
- NULL
- Component Denominator
- Creatinine
LP32035-5
- Component Denominator Core
- Creatinine
LP32035-5
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- SRto
LP6868-6
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Urine
LP7681-2
- System Core
- Urine
LP7681-2
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Glycylprolin/kreatinin: |
| el-GR | Greek (Greece) | Γλυκυλ-προλίνη/Κρεατινίνη: Synonyms: CHEM Pt Qn SRto Γλυκυλ-προλίνη Κρεατινίνη Ούρα |
| es-ES | Spanish (Spain) | Glicilprolina/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Glicilprolina / Creatinina: |
| fr-FR | French (France) | Glycylproline/créatinine: |
| it-IT | Italian (Italy) | Glicile-proline/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
| nl-NL | Dutch (Netherlands) | glycylproline/creatinine: Synonyms: kreatinine |
| pl-PL | Polish (Poland) | Glicyloprolina/kreatynina: |
| tr-TR | Turkish (Turkey) | Glisilprolin/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 甘氨酰脯氨酸/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| umol/mmol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://