79596-3
D-serine/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP201661-8 D-serine
D-serine (D-ser) is a major endogenous NMDA receptor co-agonist that specifically activates pre-synaptic NMDA receptors. D-ser is produced from L-serine by the enzyme serine racemase. Altered D-ser concentration may be associated with a number of central nervous disorders, including schizophrenia, aging, Alzheimer's disease, anxiety, cerebellar ataxia, Parkinson's disease, neuropathic pain and depression. Increasing the level of CNS D-ser by direct supplementation, or increasing production or decreasing breakdown of D-ser is being studied as a treatment option for conditions such as schizophrenia and Parkinson's disease.
PMID: 22987851
Source: Regenstrief LOINC,
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- D-serine/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- D-serine/Creat Ur-sRto
- Display Name
- D-serine/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- D-serine/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79605-2 | R- and S-beta aminoisobutyrate and D- and L-serine panel - Urine |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | D-serina/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | D-serina / Creatinina: |
| fr-FR | French (France) | D-sérine/créatinine: |
| it-IT | Italian (Italy) | D-serina/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
| nl-NL | Dutch (Netherlands) | D-serine/creatinine: Synonyms: kreatinine |
| tr-TR | Turkish (Turkey) | D-serin/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | D-丝氨酸/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| umol/mmol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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