Version 2.77

Part Description

LP201662-6   L-serine
L-serine (L-ser) is an amino acid that plays a central role in cellular proliferation and is the major source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. L-ser is converted to D-ser by serine racemase. Altered CNS D-ser levels have been associated with a variety of neurologic conditions, including schizophrenia and Parkinson's disease. L-ser also plays a specific role in the CNS, and patients with defects of L-ser synthesis have significant neurological impairment. Two enzyme defects linked to L-ser synthesis have been discovered: 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency and phosphoserine phosphatase (PSP) deficiency. Patients with 3-PGDH deficiency can have significant neurologic impairment, including congenital microcephaly and seizures associated with decreased white matter volume and myelination, and L-ser supplementation has been used to treat the seizures in this patient population. PSP deficiency has only been identified in one patient, whose symptoms also improved with L-ser treatment. PMID: 12534373 Source: Regenstrief LOINC,

Fully-Specified Name

Component
L-serine
Property
SCnc
Time
Pt
System
CSF
Scale
Qn
Method

Additional Names

Short Name
L-serine CSF-sCnc
Display Name
L-serine (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
L-serine, Spinal fluid

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56
Change Reason
Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
79586-4 R- and S-beta aminoisobutyrate and D- and L-serine panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) L-serina:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) L-serina:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-FR French (France) L-sérine:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
it-IT Italian (Italy) L-serina:SCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) L-serine:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
tr-TR Turkish (Turkey) L-serin:SubKons:Zmlı:BOS:Kant:
zh-CN Chinese (China) L-丝氨酸:物质的量浓度:时间点:脑脊液:定量型:
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Ser 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 左 左侧 左侧（Left，L） 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

Example Units

Unit Source
umol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79601-1