Version 2.77

Part Descriptions

LP201670-9   N,N'-dimethylarginine
Dimethylarginines are endogenous analogues of L-arginine. N,N-dimethylarginine (also known as asymmetrical dimethylarginine or ADMA) and N,N'-dimethylarginine (symmetrical dimethylarginine or SDMA) both inhibit cellular L-arginine uptake, and ADMA also competitively inhibits nitric oxide (NO) synthases. ADMA is predominantly degraded by the enzyme dimethylarginine dimethylaminohydrolase, while SDMA is primarily excreted by the kidney. PMID: 25245031 ADMA and NO play a pivotal role in endothelial dysfunction, and elevated ADMA levels may be associated with a higher risk of cardiovascular disease. SDMA has not been associated with cardiovascular disease but correlates with both measured and estimated glomerular filtration rate and is a marker of renal function. PMID: 26021436 Source: Regenstrief LOINC,

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component
N,N'-dimethylarginine/Creatinine
Property
SRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
N,N'-dimethylarginine/Creat Ur-sRto
Display Name
N,N'-dimethylarginine/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info
N,N'-dimethylarginine/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56
Change Reason
Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) N,N'-dimetilarginina/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) N, N'-dimetilarginina / Creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-FR French (France) N,N'-diméthylarginine/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
it-IT Italian (Italy) N,N'-dimetilarginina/Creatinina:Srto:Pt:Urine:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza
nl-NL Dutch (Netherlands) N,N'-dimethylarginine/creatinine:molaire verhouding:moment:urine:kwantitatief:
Synonyms: kreatinine
tr-TR Turkish (Turkey) N,N'-dimetilarjinin/Kreatinin:SOrn:Zmlı:İdrar:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) N,N'-二甲基精氨酸/肌酐:物质的量比率:时间点:尿液:定量型:
Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 N 型 N,N''-双甲基精氨酸 UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 肌酸内酰胺

Example Units

Unit Source
umol/mmol{creat} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79639-1