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Part Description

LP203038-7   HLA-A*31:01
The human leukocyte antigen B (HLA-B; [HGNC Gene ID: 4932]) plays an important role in how the immune system recognizes and responds to pathogens. HLA-B belongs to a class of molecules that are found on the surface of most cells. These molecules are responsible for presenting peptides to immune cells. Peptides derived from normal human proteins are recognized as such, whereas foreign peptides derived from pathogens trigger an immune response. Antiepileptics with an aromatic ring, for example carbamazepine and phenytoin, interact with HLA-B*31:01 and alter the repertoire of self peptides that are presented to T lymphocytes, which activates an immune reaction known as Stevens-Johnson syndrome or toxic epidermal necrolysis. PMID: 23695185 PMID: 25099164 See https://www.pharmgkb.org/gene/PA35056 for more information and dosing guidelines for drugs impacted by HLA-B genetic variation. Source: Clinical Pharmacogenetics Implementation Consortium

LOINC Names Get Info

Fully-Specified Name
HLA-A*31:01:PrThr:Pt:Bld/Tiss:Ord:
Long Common Name
HLA-A*31:01 [Presence] in Blood or Tissue
Short Name
HLA-A*31:01 Bld/T Ql
Display Name
HLA-A*31:01 Ql (Bld/Tiss)
Consumer Name Alpha Get Info
HLA-A*31:01, Blood or tissue specimen

Part Model Get Info

  • Component
    HLA-A*31:01
    LP203038-7
    • Analyte
      HLA-A*31:01
      LP203038-7
      • Component Numerator
        HLA-A*31:01
        LP203038-7
        • Component Numerator Core
          HLA-A*31:01
          LP203038-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    NULL
     

Preferred Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MOLPATH.PHARMG
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
94855-4carBAMazepine hypersensitivity genotype panel - Blood or Tissue

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)HLA-A*31:01:Přítomnost nebo práh:Časový bod:Krev/tkáň:Ordinální:
el-GRGreek (Greece)Ανθρώπινα λευκοκυτταρικά αντιγόνα-A*31:01:PrThr:Pt:Αίμα/Ιστός:Ord:
Synonyms: A MOLPATH MOLPATH.PHARMG Ord PrThr Pt Αίμα Αίμα/Ιστός Ανθρώπινα λευκοκυτταρικά αντιγόνα Ανθρώπινα λευκοκυτταρικά αντιγόνα-A Ανθρώπινα λευκοκυτταρικά αντιγόνα-A*31:01 Ιστός
es-ESSpanish (Spain)HLA-A*31:01:PrThr:Punto temporal:Sangre o tejido:Ord:
es-MXSpanish (Mexico)HLA-A * 31:1:Presencia o umbral:Punto temporal:Sangre o tejido:Ordinal
fr-FRFrench (France)HLA-A*31:01:Présence/Seuil:Ponctuel:Sang/Tissu:Qualitatif:
it-ITItalian (Italy)HLA-A*31:01:PrThr:Pt:Sangue/Tess:Ord:
Synonyms: Farmacogenomica Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NLDutch (Netherlands)HLA-A*31:01:aanwezigheid:moment:bloed of weefsel:ordinaal:
pl-PLPolish (Poland)HLA-A*31:01:granica wykrywalności:punkt w czasie:krew lub tkanka:uporządkowany:
tr-TRTurkish (Turkey)HLA-A*31:01:MevcEşik:Zmlı:Kan/Dk:Srl:
Synonyms: Mevcut
zh-CNChinese (China)HLA-A*31:01:存在情况或阈值:时间点:全血/组织:序数型:
Synonyms: A 型 HLA 抗原;人类白细胞抗原;human leukocyte antigen 人白细胞抗原 人类白细胞抗原 人类白细胞抗原（Human Leukocyte Antigen，HLA） 人类白细胞抗原;human leukocyte antigen;HLA 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 白细胞抗原 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79712-6