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Term Description

This term was developed in collaboration with the National Institute of Health's National Eye Institute (NEI) as part of an effort to standardize the data elements collected by the National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE).

Part Descriptions

LP201235-1   Extraocular retinoblastoma classification
The Reese-Ellsworth extraocular retinoblastoma staging system applies to cancer that has spread outside of the eye, either to the tissues around the eye or to the central nervous system (CNS), bone marrow, or lymph nodes. This staging system is based on how much cancer remains after surgery to remove the tumor and whether the cancer has spread. Details of each stage in the extraocular staging system are as follows:
Stage 0 (zero) - the cancer is in the eye (called intraocular) and has not spread outside of the eye. Most retinoblastoma cases are discovered in Stage 0 and should be classified based on the International Classification for Intraocular Retinoblastoma (ICRB). Doctors recommend conservative treatment for this stage with no additional adjuvant therapy, meaning no additional treatment after surgery.
Stage I - the eye has already been removed and there is some microscopic spread to the optic nerve. These patients need adjuvant chemotherapy after surgery.
Stage II - the tumor has spread to the optic nerve or the sclera, which is the white part of the eye. Patients with this stage need adjuvant chemotherapy and possibly radiation therapy.
Stage III - the cancer has spread to the lymph nodes or the bony cavity that surrounds the eyeball. Stage III is divided into two substages called stage IIIa and stage IIIb, depending on where the tumor has spread. The treatment for this stage involves both chemotherapy and radiation therapy.
Stage IV - the tumor has spread to distant areas of the body outside the eye, via the lymphatic system and blood vessels. Stage IV is divided into substages called IVa and IVb, and IVb is further divided into IVb1, IVb2, and IVb3, depending on the location of the spread. This stage of extraocular retinoblastoma is treated with high-dose chemotherapy followed by stem cell rescue. Radiation therapy may also be used in addition to high-dose chemotherapy for some patients with stage IV disease.
http://www.cancer.gov/types/retinoblastoma/patient/retinoblastoma-treatment-pdq#link/stoc_h2_1 Source: National Cancer Institute,

LP203649-1   EYE.HX.NEI
Developed in collaboration with the National Institute of Health's National Eye Institute (NEI) as part of an effort to standardize the data elements collected by the National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE). Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Extraocular retinoblastoma classification^at final disease stage:Class:Pt:Eye.left:Ord:Reese-Ellsworth system
Long Common Name
Reese-Ellsworth Extraocular retinoblastoma classification at final disease stage Left eye
Short Name
Reese-Ells class final dis stage Eye-L

Part Model Get Info

  • Component
    Extraocular retinoblastoma classification^at final disease stage
    LP308073-8
    • Analyte
      Extraocular retinoblastoma classification
      LP201235-1
      • Component Numerator
        Extraocular retinoblastoma classification
        LP201235-1
        • Component Numerator Core
          Extraocular retinoblastoma classification
          LP201235-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      at final disease stage
      LP201232-8
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Class
    LP6795-1
  • Time
    Pt
    LP6960-1
  • System
    Eye.left
    LP7219-1
    • System Core
      Eye.left
      LP7219-1
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Reese-Ellsworth system
    LP201233-6

Normative Answer List: LL3733-4

Source: National Eye Institute
AnswerCodeScoreAnswer ID
Stage 00LA4323-7
Stage I

Stage I means that eye has already been removed and there is some microscopic spread to the optic nerve. These patients need adjuvant chemotherapy after surgery.

1LA3664-5
Stage II

Stage II means that the tumor has spread to the optic nerve or the sclera, which is the white part of the eye. Patients with this stage need adjuvant chemotherapy and possibly radiation therapy.

2LA3661-1
Stage III

means that the cancer has spread to the lymph nodes or the bony cavity that surrounds the eyeball. It is divided into two substages called stage IIIa and stage IIIb, depending on where the tumor has spread. The treatment for this stage involves both chemotherapy and radiation therapy.

3LA3657-9
Stage IV

In stage IV, the tumor has spread to distant areas of the body outside the eye, via the lymphatic system and blood vessels. Stage IV is divided into substages of IVa and IVb. Stage IVb is further divided into IVb1, IVb2, and IVb3, depending on the location of the spread. This stage of extraocular retinoblastoma is treated with high-dose chemotherapy followed by stem cell rescue.

4LA3651-2
UnknownCopyright http://snomed.info/sct ID:261665006 Unknown (qualifier value)UNKLA4489-6

Basic Attributes

Class
EYE.HX.NEI
Type
Clinical
First Released
Version 2.54
Last Updated
Version 2.54 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
el-GRGreek (Greece)Ταξινόμηση εξωφθάλμιου ρετινοβλαστώματος^στο τελικό στάδιο της νόσου:Κατηγορία:Pt:Οφθαλμός.αριστερός:Ord:Σύστημα Reese-Ellsworth
Synonyms: EYE EYE.HX EYE.HX.NEI Ord Pt Κατηγορία Οφθαλμός Οφθαλμός.αριστερός Στάδιο Στάδιο νόσου στο τελικό στάδιο της νόσου Σύστημα Reese-Ellsworth Ταξινόμηση εξωφθάλμιου ρετινοβλαστώματος
es-MXSpanish (Mexico)Clasificación del retinoblastoma extraocular ^ en la etapa final de la enfermedad:Clase:Punto temporal:Ojo izquierdo:Ordinal:Reese-Ellsworth system
it-ITItalian (Italy)Classificazione del retinoblastoma extraoculare^allo stadio finale di malattia:Classe:Pt:Occhio.sinistro:Ord:Reese-Ellsworth, sistema
Synonyms: Concetti storia NEI eyeGENE Fase Occhio Occhio Sinistro Punto nel tempo (episodio) Sistema di classificazione Reese-Ellsworth Sistema Reese-Ellsworth Stadio della malattia
zh-CNChinese (China)眼外视网膜母细胞瘤分类^最终疾病分期时:分类:时间点:眼睛.左侧:序数型:Reese-Ellsworth 系统
Synonyms: L LT Reese-Ellsworth 分期系统;Reese-Ellsworth 分期体系;里斯-埃尔斯沃思分期系统;里斯-埃尔斯沃思分期系统;里斯（瑞茜、里瑟、李斯）-埃尔斯沃思分期系统 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分级;阶段;时期 向左 向左侧 左 左侧（Left，LT，L） 左侧眼睛;左眼 左向 左边 族;种类;等;类;类别;级;纲;组 时刻;随机;随意;瞬间 最终（最后）疾病分期（阶段、分级）时（的时候）;疾病终末期（晚期、末期）时（的时候）;终末疾病分期（阶段、分级）时（的时候） 疾 疾病阶段 病 症 目;眼;眼部 眼;眼睛;眼科;眼科学与验光变量;眼科学与验光指标 眼外（眼外期）视网膜母细胞瘤（成视网膜细胞瘤、视网膜神经胶质瘤、眼癌、视网膜胚细胞瘤、视网膜母细胞肿瘤、视网膜胚母细胞瘤）分类 眼科学与视力测定变量.病史（历史纪录、历史、病史纪录） 眼科学与视力测定变量.病史（眼科病史、眼睛病史、眼部病史、HX）.NEI;NEI eyeGENE''s eye history concepts;NEI eyeGENE 病史（眼科病史、眼睛病史、眼部病史、HX）概念

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79748-0