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Part Description

LP200579-3   S-adenosylhomocysteine
S-Adenosylhomocysteine (SAH) is formed by the demethylation of S-adenosylmethionine (SAMe) and is rapidly metabolized to homocysteine. The reaction of SAH to homocysteine is catalyzed by S-adenosylhomocysteine hydrolase and is reversible with the equilibrium favoring formation of SAH. Therefore, increased levels of SAH may occur when the intracellular concentration of homocysteine increases. Since SAH is known to inhibit methylation dependent reactions, the ratio of SAMe to SAH is often used as an index of methylation status. Disturbances in the transmethylation pathway indicated by abnormal SAMe, SAH or their ratio have been reported in many neurodegenerative diseases, such as dementia, depression or Parkinson's disease. PMID: 17892439 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
S-adenosylhomocysteine:SCnc:Pt:CSF:Qn:
Long Common Name
S-adenosylhomocysteine [Moles/volume] in Cerebrospinal Fluid
Short Name
SAH CSF-sCnc
Display Name
S-adenosylhomocysteine (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
S-adenosylhomocysteine, Spinal fluid

Part Model Get Info

  • Component
    S-adenosylhomocysteine
    LP200579-3
    • Analyte
      S-adenosylhomocysteine
      LP200579-3
      • Component Numerator
        S-adenosylhomocysteine
        LP200579-3
        • Component Numerator Core
          S-adenosylhomocysteine
          LP200579-3
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
80179-5S-adenosylmethionine and S-adenosylhomocystine panel - Cerebrospinal Fluid

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)S-adenosylhomocystein:Látková koncentrace:Časový bod:Mozkomíšní mok:Kvantitativní:
el-GRGreek (Greece)S-αδενοσυλοομοκυστεΐνη:SCnc:Pt:ΕΝΥ:Qn:
Synonyms: CHEM Pt Qn S SCnc S-αδενοσυλοομοκυστεΐνη ΕΝΥ
es-ESSpanish (Spain)S-adenosilhomocistina:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)S-adenosilhomocisteína:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-FRFrench (France)S-Adénosylhomocystéine:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
it-ITItalian (Italy)S-adenosilomocisteina:SCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio)
nl-NLDutch (Netherlands)S-adenosylhomocysteïne:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
pl-PLPolish (Poland)S-adenozylohomocysteina:stężenie molowe:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy:
tr-TRTurkish (Turkey)S-adenozilhomosistein:SubKons:Zmlı:BOS:Kant:
zh-CNChinese (China)S-腺苷同型半胱氨酸:物质的量浓度:时间点:脑脊液:定量型:
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 S 型 S-腺苷基同型半胱氨酸;S-腺苷巯基丁氨酸;S-腺苷高半胱氨酸 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

Example Units

UnitSource
nmol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80174-6