Version 2.78

Term Description

This assay detects the invasion plasmid antigen H (ipaH) gene that is specific to Shigella species and enteroinvasive E. coli (EIEC) using PCR and melt curve analysis. The assay does not distinguish between Shigella and EIEC. This term was created for, but is not limited in use to, BioFire's FilmArray Gastrointestinal panel, which is intended for the detection and identification of nucleic acids from multiple bacteria, viruses, and parasites directly from stool samples from individuals with signs and/or symptoms of gastrointestinal infection.
Source: Regenstrief LOINC

Part Description

LP145956-1   Shigella species+EIEC invasion plasmid antigen H (ipaH) gene
The invasion plasmid antigen H (ipaH) gene is a multicopy gene exclusively found in all Shigella and enteroinvasive E. coli (EIEC). Shigella and EIEC both evolved from nonpathogenic Escherichia coli, and sequencing of multiple housekeeping genes indicates that EIEC is genetically related to Shigella. Shigella causes bacillary dysentery with symptoms including abdominal cramps, nausea, fever and a bloody and mucus diarrhea. By testing for the absence of lysine decarboxylase (LDC) activity and presence of the IpaH gene, Shigella and EIEC can be differentiated from non-enteroinvasive E. coli. PMID: 21901636 Source: Regenstrief LOINC, PMID: 21901636

Fully-Specified Name

Component
Shigella species+EIEC invasion plasmid antigen H (ipaH) gene
Property
PrThr
Time
Pt
System
Stool
Scale
Ord
Method
Non-probe.amp.tar

Additional Names

Short Name
Shigella sp+EIEC ipaH St NAA+non-probe
Display Name
Shigella species+EIEC invasion plasmid antigen H ipaH gene NAA+non-probe Ql (Stl)
Consumer Name Alpha Get Info
Shigella Species+EIEC Invasion Plasmid Antigen H IpaH gene, Stool

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.73
Change Reason
Changed Method from "Melt.amp.tar" to "Non-probe.amp.tar", which includes other non-probe based detection methods while still distinguishing from probe-based methods.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Observation
Common Test Rank Get Info
1343

Member of these Panels

LOINC Long Common Name
82195-9 Gastrointestinal pathogens DNA and RNA panel - Stool by NAA with non-probe detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Shigella species+EIEC-invasion plasmid antigen H (ipaH)-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Stuhl:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde
es-ES Spanish (Spain) Gen antígeno H plasmídico invasor bacterial (ipaH):PrThr:Punto temporal:Heces:Ord:Amplificación del objetivo no basado en sonda
es-MX Spanish (Mexico) Especies de Shigella + gen del antígeno H (ipaH) del plásmido invasor EIEC:Presencia o umbral:Punto temporal:Heces:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-CA French (Canada) Shigella+Escherichia coli entéroinvasif ipaH gène:Présence-Seuil:Temps ponctuel:Selles:Ordinal:Non-sonde.amplification de cible
fr-FR French (France) Shigella+Escherichia coli entéroinvasif ipaH gène:Présence/Seuil:Ponctuel:Selle:Qualitatif:Non-PCR amplification de cible
it-IT Italian (Italy) Specie shigella e Escherichia Coli enteroinvasive antigene H plasmidico di invasione batterica (ipaH), gene:PrThr:Pt:Feci:Ord:Non-sonda.amp.tar
Synonyms: Amplificazione target non basata su sonda Gene di antigene H plasmidico di invasione batteri Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
zh-CN Chinese (China) 志贺菌+肠侵袭性大肠埃希菌侵袭质粒抗原 H (ipaH) 基因:存在情况或阈值:时间点:大便:序数型:非探针法.基因扩增.靶向
Synonyms: Ag H 型 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 便;大肠运动;排便;粪便;肠运动 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 志贺氏杆菌 志贺氏杆菌属 志贺氏细菌性痢疾 志贺氏菌属 志贺氏菌病 志贺氏菌痢疾 志贺菌 志贺菌属 志贺菌属（志贺菌、志贺氏菌属、志贺氏菌）+EIEC 侵袭质粒抗原 H (ipaH) 基因;细菌侵袭质粒抗原 H (ipaH) 基因;细菌入侵质粒抗原 H (ipaH) 基因;细菌侵袭性质粒抗原 H (ipaH) 基因;invasion plasmid antigen H;ipaH;侵袭性质粒抗原 H;侵袭质粒抗原 H;入侵质粒抗原 H 志贺菌病 志贺菌痢疾 扩增型 扩增性 抗体原 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针 遗传基因;遗传因子;吉恩;生物基因

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