80549-9
Sulfamethoxazole [Mass/volume] in DBS
Active
Term Description
Dried blood spot (DBS) specimens have been used for therapeutic drug monitoring (TDM) across several classes of drugs including antimicrobials, anticonvulsants and immunosuppressants. DBS specimens are useful for TDM in infants and children due to the small sample volume required. DBS specimens are also useful for outpatient TDM in adults who have been trained to collect their own DBS because most analytes are relatively stable in DBS and the DBS card does not require specialized transportation. PMID: 25204403
Part Description
LP14550-5 Sulfamethoxazole
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole, which is also known as Bactrim or Septrin. It can be used as an alternative to amoxicillin -based antibiotics to treat sinusitis. Mechanism of action:Sulfonamides are structural anologs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells.
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Source: Wikipedia,
Sulfamethoxazole (Wikipedia)
LOINC Names Get Info
- Fully-Specified Name
- Sulfamethoxazole:
MCnc: Pt: Bld.dot: Qn: - Long Common Name
- Sulfamethoxazole [Mass/volume] in DBS
- Short Name
- Sulfamethoxazole DBS-mCnc
- Display Name
- Sulfamethoxazole (DBS) [Mass/Vol]
- Consumer Name Alpha Get Info
- Sulfamethoxazole, Dried blood spot
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.61 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Sulfamethoxazol: |
| el-GR | Greek (Greece) | Σουλφαμεθοξαζόλη: Synonyms: Bld.dot DRUG/TOX MCnc Pt Qn Αίμα Σουλφαμεθοξαζόλη |
| es-ES | Spanish (Spain) | Sulfametoxazol: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Sulfametoxazol: |
| et-EE | Estonian (Estonia) | Sulfametoksasool: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Sulfaméthoxazole: |
| fr-FR | French (France) | Sulfaméthoxazole: |
| fr-BE | French (Belgium) | Sulfaméthoxazole: |
| it-IT | Italian (Italy) | Sulfametossazolo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue Spot sangue secco |
| nl-NL | Dutch (Netherlands) | sulfamethoxazol: |
| ru-RU | Russian (Russian Federation) | Сульфаметоксазол: Synonyms: Количественный Кровь Кровь сухая капля Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | Sulfametoksazol: |
| zh-CN | Chinese (China) | 磺胺甲噁唑: Synonyms: SMX; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
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