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Term Description

Dried blood spot (DBS) specimens have been used for therapeutic drug monitoring (TDM) across several classes of drugs including antimicrobials, anticonvulsants and immunosuppressants. DBS specimens are useful for TDM in infants and children due to the small sample volume required. DBS specimens are also useful for outpatient TDM in adults who have been trained to collect their own DBS because most analytes are relatively stable in DBS and the DBS card does not require specialized transportation. PMID: 25204403

Part Descriptions

LP17236-8   cloZAPine
Clozapine (sold as Clozaril ®, Leponex ®, Fazaclo ®) was the first of the atypical antipsychotics to be developed. It was approved by the United States Food and Drug Administration (FDA) in 1989 and is the only FDA-approved medication indicated for treatment-resistant schizophrenia and for reducing the risk of suicidal behaviour in patients with schizophrenia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Clozapine (Wikipedia)

LP17236-8   cloZAPine
A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent. Source: National Library of Medicine, MeSH 2006

LOINC Names Get Info

Fully-Specified Name
cloZAPine:MCnc:Pt:Bld.dot:Qn:
Long Common Name
cloZAPine [Mass/volume] in DBS
Short Name
cloZAPine DBS-mCnc
Display Name
cloZAPine (DBS) [Mass/Vol]
Consumer Name Alpha Get Info
cloZAPine, Dried blood spot

Part Model Get Info

  • Component
    cloZAPine
    LP17236-8
    • Analyte
      cloZAPine
      LP17236-8
      • Component Numerator
        cloZAPine
        LP17236-8
        • Component Numerator Core
          cloZAPine
          LP17236-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Bld.dot
    LP21304-8
    • System Core
      Bld.dot
      LP21304-8
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.61 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Klozapin:Hmotnostní koncentrace:Časový bod:Suchá krevní kapka (DBS):Kvantitativní:
el-GRGreek (Greece)Κλοζαπίνη:MCnc:Pt:Bld.dot:Qn:
Synonyms: Bld.dot DRUG/TOX MCnc Pt Qn Αίμα Κλοζαπίνη
es-ESSpanish (Spain)Clozapina:Concentración de masa:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)clozapina:Concentración de masa:Punto temporal:DBS:Cuantitativo:
et-EEEstonian (Estonia)Klosapiin:MCnc:Pt:Vereplekk:Qn:
Synonyms: Juhuslik Kvantitatiivne Veri
fr-CAFrench (Canada)Clozapine:Concentration de masse:Temps ponctuel:Sang sur papier filtre:Quantitatif:
fr-FRFrench (France)Clozapine:Masse/Volume:Ponctuel:Sang buvard:Numérique:
fr-BEFrench (Belgium)Clozapine:Concentration de masse:Temps ponctuel:Sang sur papier filtre:Quantitatif:
it-ITItalian (Italy)Clozapina:MCnc:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue Spot sangue secco
nl-NLDutch (Netherlands)clozapine:massa/volume:moment:gedroogde bloedspot:kwantitatief:
ru-RURussian (Russian Federation)Клозапин:МассКонц:ТчкВрм:Кр.Сух.капл:Колич:
Synonyms: Количественный Кровь Кровь сухая капля Массовая концентрация Точка во времени;Момент
tr-TRTurkish (Turkey)Klozapine:KütlKons:Zmlı:Kan.nokta:Kant:
zh-CNChinese (China)氯氮平:质量浓度:时间点:全血.斑点:定量型:
Synonyms: 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 氯扎平 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

UnitSource
ug/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80556-4