Version 2.77

Term Description

Dried blood spot (DBS) specimens have been used for therapeutic drug monitoring (TDM) across several classes of drugs including antimicrobials, anticonvulsants and immunosuppressants. DBS specimens are useful for TDM in infants and children due to the small sample volume required. DBS specimens are also useful for outpatient TDM in adults who have been trained to collect their own DBS because most analytes are relatively stable in DBS and the DBS card does not require specialized transportation. PMID: 25204403
Source: Regenstrief LOINC

Part Description

LP16098-3   cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. PMID: 19545653 Source: Regenstrief LOINC, PMID: 19545653

Fully-Specified Name

Component
cycloSPORINE
Property
MCnc
Time
Pt
System
Bld.dot
Scale
Qn
Method

Additional Names

Short Name
cycloSPORINE DBS-mCnc
Display Name
cycloSPORINE (DBS) [Mass/Vol]
Consumer Name Alpha Get Info
cycloSPORINE, Dried blood spot

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.66
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Ciclosporina:Concentración de masa:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) cicloesporino:Concentración de masa:Punto temporal:DBS:Cuantitativo:
et-EE Estonian (Estonia) Tsüklosporiin:MCnc:Pt:Vereplekk:Qn:
Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA French (Canada) Cyclosporine:Concentration de masse:Temps ponctuel:Sang sur papier filtre:Quantitatif:
fr-FR French (France) Ciclosporine:Masse/Volume:Ponctuel:Sang buvard:Numérique:
fr-BE French (Belgium) Cyclosporine:Concentration de masse:Temps ponctuel:Sang sur papier filtre:Quantitatif:
it-IT Italian (Italy) Ciclosporina:MCnc:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue Spot sangue secco
nl-NL Dutch (Netherlands) ciclosporine:massa/volume:moment:gedroogde bloedspot:kwantitatief:
ru-RU Russian (Russian Federation) Циклоспорин:МассКонц:ТчкВрм:Кр.Сух.капл:Колич:
Synonyms: Количественный Кровь Кровь сухая капля Массовая концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Siklosporin:KütlKons:Zmlı:Kan.nokta:Kant:
zh-CN Chinese (China) 环孢菌素:质量浓度:时间点:全血.斑点:定量型:
Synonyms: 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 环孢霉素A; 山地明环孢灵; 环孢多肽A; 环孢素; 赛斯平; 环孢菌素; 环孢菌素A; 环孢素A;山地明;环孢多肽;环孢抑制剂;环孢灵;环孢霉素;环孢霉素A;环孢素;Cyclosporine;Cyclosporin; Restasis; Cyclosporine A; cyclosporin A; Antibiotic S 7481F1; 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonameth 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

Unit Source
ug/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80561-4