80561-4
cycloSPORINE [Mass/volume] in DBS
Active
Term Description
Dried blood spot (DBS) specimens have been used for therapeutic drug monitoring (TDM) across several classes of drugs including antimicrobials, anticonvulsants and immunosuppressants. DBS specimens are useful for TDM in infants and children due to the small sample volume required. DBS specimens are also useful for outpatient TDM in adults who have been trained to collect their own DBS because most analytes are relatively stable in DBS and the DBS card does not require specialized transportation. PMID: 25204403
Source: Regenstrief LOINC
Part Description
LP16098-3 cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. PMID: 19545653
Source: Regenstrief LOINC, PMID: 19545653
Fully-Specified Name
- Component
- cycloSPORINE
- Property
- MCnc
- Time
- Pt
- System
- Bld.dot
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- cycloSPORINE [Mass/volume] in DBS
- Short Name
- cycloSPORINE DBS-mCnc
- Display Name
- cycloSPORINE (DBS) [Mass/Vol]
- Consumer Name Alpha Get Info
- cycloSPORINE, Dried blood spot
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.66
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Ciclosporina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | cicloesporino: |
et-EE | Estonian (Estonia) | Tsüklosporiin: Synonyms: Juhuslik Kvantitatiivne Veri |
fr-CA | French (Canada) | Cyclosporine: |
fr-FR | French (France) | Ciclosporine: |
fr-BE | French (Belgium) | Cyclosporine: |
it-IT | Italian (Italy) | Ciclosporina: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue Spot sangue secco |
nl-NL | Dutch (Netherlands) | ciclosporine: |
ru-RU | Russian (Russian Federation) | Циклоспорин: Synonyms: Количественный Кровь Кровь сухая капля Массовая концентрация Точка во времени; |
tr-TR | Turkish (Turkey) | Siklosporin: |
zh-CN | Chinese (China) | 环孢菌素: Synonyms: 全血斑点(滤纸); |
Example Units
Unit | Source |
---|---|
ug/L | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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