8062-2

Cardiolipin Ab [Units/volume] in Serum

Active

Part Descriptions

LP14126-4   Cardiolipin
Cardiolipin (bisphosphatidyl glycerol) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid. It is typically present in metabolically active cells of the heart and skeletal muscle. It has also been observed in certain bacterial membranes. It serves as an insulator and stabilizes the activity of protein complexes important to the electron transport chain. Cardiolipin is a double phospholipid because it has four fatty acid tails, instead of the usual two. Barth syndrome, a rare genetic disorder, is a mutation in the gene coding for tafazzin, an enzyme involved in the biosynthesis of cardiolipin. Females heterozygous for the trait are not affected. Individuals with this condition have abnormal mitochondria and they cannot sustain adequate production of ATP. Cardiomyopathy and general weakness are common to these patients. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Cardiolipin (Wikipedia)

LP21333-7   Cardiolipin Ab
Anti-cardiolipin antibodies (ACA) are antibodies often directed against cardiolipin and found in several diseases including syphilis, antiphospholipid syndrome, livedoid vasculitis, vertebrobasilar insufficiency, Behçet's syndrome, idiopathic spontaneous abortion, and systemic lupus erythematosus(SLE). They are a form of anti-mitochondrial antibody. In SLE, The anti-DNA antibodies and anti-cardiolipin act independently. In rheumatoid arthritis with systemic sclerosis (scleroderma) these antibodies may tie two conditions together.
Anti-cardiolipin antibodies can be classified in two ways:
As IgM, IgG or IgA
As β2-glycoprotein dependent or independent
In autoimmune disease ACA are beta-2 glycoprotein dependent
syphilis ACA are beta-2 glycoprotein independent and can be assayed using the VDRL test Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

Fully-Specified Name

Component

Cardiolipin Ab

Property

ACnc

Time

Pt

System

Ser

Scale

Qn

Method

Additional Names

Long Common Name

Cardiolipin Ab [Units/volume] in Serum

Short Name

Cardiolipin Ab Ser-aCnc

Display Name

Cardiolipin Ab Qn (S)

Consumer Name Alpha Get Info

Cardiolipin antibody, Blood

Basic Attributes

Class

COAG

Type

Laboratory

First Released

Version 1.0h(2)

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Both

Common Test Rank Get Info

5516

Language Variants Get Info

Related Names

• ABS
• Aby
• ACA
• aCL
• Antby
• Anti
• Antibodies
• Antibody
• Anticardiolipin
• Arbitrary concentration
• Autoantibodies
• Autoantibody
• Cardio
• Cardiolip
• Cardiolipn
• Cardiolpn
• CL
• COAGULATION
• Hematology
• Heme
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Serum
• SR

Example Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.

CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=8062-2

LOINC Copyright

Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.