80643-0
Gadolinium [Mass/mass] in Tissue
Active
Term Description
Due to its paramagnetic properties, chelated gadolinium is commonly employed as contrast media for magnetic resonance imaging (MRI) and computer tomography (CT) scanning. Gadolinium is eliminated primarily by the renal filtration. In healthy subjects with normal renal function, the plasma half-life of gadolinium is approximately 90 minutes. Patients with reduced renal function exhibit increased gadolinium excretion half-life and may be affected by nephrogenic systemic fibrosis (NSF). In this syndrome, prolonged retention of gadolinium is thought to allow the gadolinium cation to dissociate from its synthetic organic chelator and deposit predominantly in the skin, although other organs may be affected as well. These patients are often severely debilitated by progressive skin thickening and tightening. Fibrosis of skeletal muscle, lungs, liver, testes, and myocardium have also been observed, often with fatal results. Three hemodialysis treatments are required to substantially remove gadolinium from patients with impaired renal function; peritoneal dialysis is not effective.
Part Descriptions
LP17766-4 Gadolinium
Gadolinium. An element of the rare earth family of metals. It has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
Source: National Library of Medicine, MeSH 2006
LP17766-4 Gadolinium
Gadolinium is a long-used contrast agent used for magnetic resonance imaging (MRI) studies. It is a lanthanide series metal, which is administered in chelated form to minimize its natural cytotoxicity. Most of administered gadolinium chelate is excreted promptly in urine with a half life of 60-90 minutes. Lower doses used recently have alleviated concern of kidney and liver damage, although nephrogenic systemic fibrosis is still a concern. PMID: 29977584
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Gadolinium:
MCnt: Pt: Tiss: Qn: - Long Common Name
- Gadolinium [Mass/mass] in Tissue
- Short Name
- Gadolinium Tiss-mCnt
- Display Name
- Gadolinium (Tiss) [Mass/Mass]
- Consumer Name Alpha Get Info
- Gadolinium, Tissue
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.63 (MAJ)
- Change Reason
- Updated System from "Tissue" to "Tiss" to be consistent with other laboratory tissue terms.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gadolinium: |
| el-GR | Greek (Greece) | Γαδολίνιο: Synonyms: DRUG/TOX MCnt Pt Qn Γαδολίνιο Ιστός |
| es-ES | Spanish (Spain) | Gadolinio: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Gadolinio: |
| fr-CA | French (Canada) | Gadolinium: |
| fr-FR | French (France) | Gadolinium: |
| fr-BE | French (Belgium) | Gadolinium: |
| it-IT | Italian (Italy) | Gadolinium: Synonyms: Contenuto di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Tessuto & |
| nl-NL | Dutch (Netherlands) | gadolinium: |
| pl-PL | Polish (Poland) | Gadolin: Synonyms: Gd |
| ru-RU | Russian (Russian Federation) | Гадолиний: Synonyms: Количественный Масса содержание Ткань и мазки Точка во времени; |
| tr-TR | Turkish (Turkey) | Gadolinium: |
| zh-CN | Chinese (China) | 钆: Synonyms: GADO; |
Example Units
| Unit | Source |
|---|---|
| ug/g | Example UCUM Units |
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LOINC Copyright
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