80689-3

HIV 1 RNA reverse transcriptase and protease and integrase gene mutations detected [Identifier] in Plasma by Sequencing

Active

Part Description

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: HIV 1 RNA reverse transcriptase & protease & integrase gene mutations detected:Prid:Pt:Plas:Nom:Sequencing
Long Common Name: HIV 1 RNA reverse transcriptase and protease and integrase gene mutations detected [Identifier] in Plasma by Sequencing
Short Name: HIV 1 RNA RT + PR + IN Mut Det Plas Seq
Display Name: HIV 1 RNA reverse transcriptase and protease and integrase gene mutations detected Sequencing Nom (P)
Consumer Name Alpha Get Info: HIV 1 RNA Reverse Transcriptase and Protease and Integrase gene variant analysis, Blood

Part Model Get Info

Component
HIV 1 RNA reverse transcriptase & protease & integrase gene mutations detected
LP228629-4
- Analyte
  HIV 1 RNA reverse transcriptase & protease & integrase gene mutations detected
  LP228629-4
  - Component Numerator
    HIV 1 RNA reverse transcriptase & protease & integrase gene mutations detected
    LP228629-4
    - Component Numerator Core
      HIV 1 RNA reverse transcriptase & protease & integrase gene
      LP207668-7
    - Component Numerator Core Suffix
      mutations detected
      LP32420-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Prid
LP6850-4
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Plas
LP7479-1
- System Core
  Plas
  LP7479-1
- Super System
  NULL
Scale
Nom
LP7750-5
Method
Sequencing
LP150045-5

Example Answer List: LL2436-5

Source: Laboratory Corporation of America

Answer	Code	Score	Answer ID
V234L HIV mutation in the integrase (IN) coding region			LA24453-5
K13K/E HIV mutation in the reverse transcriptase (RT) coding region			LA19752-7
K20R HIV mutation in the reverse transcriptase (RT) coding region			LA19753-5
E28D HIV mutation in the reverse transcriptase (RT) coding region			LA19754-3
M41M/L HIV mutation in the reverse transcriptase (RT) coding region			LA19755-0
G359S HIV mutation in the reverse transcriptase (RT) coding region			LA25848-5
V35I HIV mutation in the reverse transcriptase (RT) coding region			LA25847-7
K14R HIV mutation in the integrase (IN) coding region			LA19756-8
V31I HIV mutation in the integrase (IN) coding region			LA19757-6
G193E HIV mutation in the integrase (IN) coding region			LA24451-9
D288N HIV mutation in the integrase (IN) coding region			LA24454-3
I62V HIV mutation in the protease (PR) coding region			LA19758-4
Q18K HIV mutation in the protease (PR) coding region			LA25851-9
E35D HIV mutation in the protease (PR) coding region			LA25852-7

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 6046

Member of these Panels

LOINC	Long Common Name
75622-1	HIV 1 and 2 tests - Meaningful Use set

Language Variants Get Info

Tag	Language	Translation
ar-JO	Arabic (Jordan)	الكشف عن طفرات في جينات النسخ العكسي والبروتياز والإنزيم المدمج لفيروس نقص المناعة المكتسب نمط 1 في البلازما ( بتقنية التسلسل )
cs-CZ	Czech (Czechia)	HIV 1 RNA reverzní transkriptáza+proteáza+integráza genové mutace detekované:Přítomnost nebo identita:Časový bod:Plazma:Nominální:Sekvenace
de-DE	German (Germany)	HIV-1 RNA Reverse Transcriptase & Protease & Integrase-Gene Mutationen entdeckt:Nachweis oder Identität:Zeitpunkt:Plasma:Nominal:Sequenzierung
el-GR	Greek (Greece)	Γονίδιο αντίστροφης μεταγραφάσης & πρωτεάσης & ιντεγκράσης του RNA του ιού της ανθρώπινης ανοσοανεπάρκειας 1 ανιχνευθείσες μεταλλάξεις:Prid:Pt:Πλάσμα:Nom:Αλληλούχιση Synonyms: ABXBACT HIV 1 Nom Prid Pt RNA RNA ιού της ανθρώπινης ανοσοανεπάρκειας 1 Αλληλούχιση ανιχνευθείσες μεταλλάξεις Γονίδιο Γονίδιο αντίστροφης μεταγραφάσης & πρωτεάσης & ιντεγκράσης του RNA του ιού της ανθρώπινης ανοσοανεπάρκειας 1 Ιός ανθρώπινης ανοσοανεπάρκειας Μεταλλάξεις Πλάσμα
es-ES	Spanish (Spain)	Gen de la integrasa, proteasa y transcriptasa inversa del RNA del HIV 1 Detección de mutaciones:Presencia o identidad:Punto temporal:Plasma:Nom:Secuenciación
es-MX	Spanish (Mexico)	Se detectaron mutaciones en los genes de la transcriptasa inversa, proteasa e integrasa del ARN del VIH 1:Presencia o identidad:Punto temporal:Plasma:Nominal:Secuenciación
fr-FR	French (France)	VIH-1 ARN gènes réverse transcriptase et protéase et intégrase mutations détectées:Identification:Ponctuel:Plasma:Résultat nominal:Séquençage
it-IT	Italian (Italy)	HIV 1 proviral,RNA gene trascrittasi inversa& proteasi & integrasi, mutazioni identificate:Prid:Pt:Plasma:Nom:Sequenziamento Synonyms: Plasma Presenza o Identità Punto nel tempo (episodio) RNA dell''HIV 1 Suscettibilità agli antibiotici
nl-NL	Dutch (Netherlands)	HIV 1 RNA reverse transcriptase & protease & integrase gen gedetecteerde mutaties:identificator:moment:plasma:nominaal:sequencing
pl-PL	Polish (Poland)	HIV-1 RNA odwrotna transkryptaza & proteaza & integraza gen wykryte mutacje:obecność lub identyfikacja:punkt w czasie:osocze:skala nominalna:sekwencjonowanie Synonyms: Gen odwrotnej transkryptazy, proteazy i integrazy RNA ludzkiego wirusa niedoboru odporności typu 1 Ludzki wirus niedoboru odporności Ludzki wirus niedoboru odporności typu 1 RNA ludzkiego wirusa niedoboru odporności typu 1 wynik kategorialny
uk-UA	Ukrainian (Ukraine)	Виявлені мутації генів ВІЛ1 РНК зворотньої транскриптази&протеази & інтегрази:Наявність або Ідентифікація:МоментЧасу:Плазма:Категорійно:Секвенування Synonyms: AIDS; ANTIBIOTIC SUSCEPTIBILITIES; high-throughput sequencing; HIV 1 RNA RT + PR + IN; HIV type 1; HIV type I; HIV1; HTS; Human immunodeficiency virus; i; ID; Identity or presence; Infectious Disease; InfectiousDisease; Mut; Mut Det; Mutation; Muts; Next generation sequencing; NGS; Nominal; Pl; Plasma; Plsm; Point in time; PR; Random; REV; Ribonucleic acid; RT
zh-CN	Chinese (China)	HIV 1 型 RNA 逆转录酶与蛋白酶与整合酶基因已检出的突变:存在与否或特征标识:时间点:血浆:名义型:序列测定 Synonyms: Ⅰ AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） RNA（核糖核酸）逆转录酶（反转录酶、逆录酶、RT）与蛋白酶（Prot）与整合酶（IN）基因 HIV1 RNA HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I RT RTase 倒倒的倒转倒转的分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答反向反向的反常反常的反的反相反相的反转录酶存在;存在与否;特征标识;身份;身份标识已发现的突变序列分析;测序抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类时刻;随机;随意;瞬间朊酶核糖核酸;Ribonucleic acid 相反相反的突变突变类;基因突变蛋白质酵素逆逆的逆转录酶（Reverse transcriptase，RT）遗传基因;遗传因子;吉恩;生物基因颠倒颠倒的

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.