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Part Descriptions

LP200632-0   Cells.CD4-CD8-
T-cell receptors (TCR) are composed of two polypeptide chains. The majority of TCRs have an alpha and a beta chain, but some have a gamma and delta chain. Most T cells that express TCR alpha beta are either CD4+ or CD8+. However, double-negative T cells, which are both CD4- and CD8-, also express TCR alpha beta. Double-negative T cells are associated with and may play a role in the pathogenesis of certain autoimmune and inflammatory conditions, including systemic lupus erythematosus (SLE) and autoimmune lymphoproliferative syndrome. PMID: 25825451 Source: Regenstrief LOINC, PMID: 25825451

LP17729-2   CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

LP14443-3   CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Cells.CD4-CD8-/Cells.CD3+TCR alpha beta+:NFr:Pt:Bld:Qn:
Long Common Name
CD4-CD8-/Cells.CD3+TCR alpha beta+ in Blood
Short Name
CD4-CD8-/CD3+TCR A-B+ NFr Bld
Display Name
CD4-CD8-/Cells.CD3+TCR alpha beta+ (Bld)
Consumer Name Alpha Get Info
CD4-CD8-/Cells.CD3+TCR alpha beta+, Blood

Part Model Get Info

  • Component
    Cells.CD4-CD8-/Cells.CD3+TCR alpha beta+
    LP445246-4
    • Analyte
      Cells.CD4-CD8-/Cells.CD3+TCR alpha beta+
      LP445246-4
      • Component Numerator
        Cells.CD4-CD8-
        LP200632-0
        • Component Numerator Core
          Cells.CD4-CD8-
          LP200632-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Cells.CD3+TCR alpha beta+
        LP444760-5
        • Component Denominator Core
          Cells.CD3+TCR alpha beta+
          LP444760-5
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    NFr
    LP6838-9
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
101414-1Lymphocyte TCR alpha beta double negative subsets panel - Blood

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Buňky.CD4-CD8-/100 buněk.CD3+TCR alfa beta+:Početní podíl:Časový bod:Krev:Kvantitativní:
es-MXSpanish (Mexico)Cells.CD4-CD8- / 100 Cells.CD3 + TCR alpha beta +:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
es-ESSpanish (Spain)Células CD4-CD8-/Células CD3+TCR alfa beta+:Fracción numérica:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
fr-FRFrench (France)CD4-CD8-/CD3+TCR alpha bêta+:Fraction de nombres:Ponctuel:Sang:Numérique:
it-ITItalian (Italy)Cellule.CD4-CD8-/Cellule.CD3+TCR alfa beta+:NFr:Pt:Sangue:Qn:
Synonyms: Cellule CD3 Cellule CD3+TCR Cellule CD3+TCR alfa beta+ Cellule CD4 Cellule CD4+CD8+ Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
nl-NLDutch (Netherlands)cellen.CD4-CD8-/100 cellen.CD3+TCR alfa beta+:getalsfractie:moment:bloed:kwantitatief:
pl-PLPolish (Poland)Komórki.CD4-CD8-/komórki.CD3+TCR alfa beta+:frakcja liczbowa:punkt w czasie:krew:ilościowy:
Synonyms: CD4 CD8 komórki CD3+TCR alfa beta+ Komórki CD4 Komórki CD4+CD8+ Komórki CD4-CD8- Receptor komórek T alfa beta
zh-CNChinese (China)细胞.CD4-CD8-/细胞.CD3+TCR alpha beta+:计数型分数:时间点:全血:定量型:
Synonyms: B CD3+TcR细胞;CD3+细胞受体细胞;细胞.CD3+T细胞受体 CD3+T细胞受体 Alpha Beta+细胞;CD3+T细胞受体 αβ+细胞;CD3+TcR Alpha Beta+细胞;CD3+TcR αβ+细胞;细胞.CD3+T细胞受体 alpha beta+;细胞.CD3+TcR αβ+ CD3细胞 CD4+CD8+细胞 CD4细胞 L3T4 Leu2 Leu-2 Leu3 Leu-3 Leu4;Leu-4;T3 T 细胞受体 A-B;T 细胞受体 alpha beta;T 细胞受体 α-β;TcR A-B;TcR α-β T4 T-4 T8 T-8 Tsuppressor W3/25 α β 发现于 抑制性 T-细胞/细胞毒性 T-细胞、一些 NK 细胞之上。与一些成熟 T-细胞肿瘤和大颗粒淋巴细胞增多症相关 发现于辅助 T-细胞；微弱表达于单核细胞。与相关。一些成熟 T-细胞肿瘤，包括大多数情况下的 T-细胞慢性淋巴细胞白血病/前淋巴细胞白血病、外周 T-细胞淋巴瘤、成人 T-细胞白血病/淋巴瘤以及 Sézary 综合征（T 细胞红皮病）/蕈样肉芽肿（mycosis fungoides）。 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抑制性 T 细胞 抑制性 T-细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞.CD3+TCR αβ+ 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液 诱导 T 细胞 诱导性 T 细胞 贝塔 辅助 T 细胞 辅助诱导 T 细胞 辅助诱导物 T 细胞 阿尔法

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80699-2