Version 2.80

Part Descriptions

LP100021-7   Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively. Source: Regenstrief Help

LP200619-7   Cells.CD27+CD45RA-
CD27 and CD45RA are both lymphocyte cell surface markers that can be used to classify T-cells into various subsets. Expression of CD27 is characteristic of naive T-cells and some subsets of memory T-cells, while lack of CD27 is characteristic of effector T-cells. PMID: 19454729. CD45RA is characteristic of resting or naive T-cells. Cells expressing both CD27+CD45RA+ are undifferentiated (naive), CD27+CD45RA- T-cells are at an early stage of differentiation and exhibit characteristics of memory T cells, whereas CD27-CD45RA- T-cells are highly differentiated and have characteristics of both memory and effector T-cells. PMID: 12023349 PMID: 21788446 Source: Regenstrief LOINC

LP17729-2   CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

LP20086-2   CD45RA
Found on Naive helper T-cells, B-cells and Granulocytes
Associated with some T-cell lymphomas and some mature B-cell lymphomas Source: Regenstrief LOINC

Fully-Specified Name

Component
Cells.CD27+CD45RA-/Cells.CD3+CD8+
Property
NFr
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Long Common Name
CD27+CD45RA- cells/CD3+CD8+ (T8 suppressor cells) cells in Blood
Short Name
CD27+CD45RA- cells/CD3+CD8+ Cll NFr Bld
Display Name
CD27+CD45RA- cells/CD3+CD8+ (T8 suppressor cells) cells (Bld)
Consumer Name Alpha Get Info
CD27+CD45RA- cells/CD3+CD8+ (T8 Suppressor Cells) Cells, Blood

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
80720-6 T-cell naive and memory and effector (CD27 and CD45RA) subsets panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κύτταρα.CD27+CD45RA-/Κύτταρα.CD3+CD8+:NFr:Pt:Αίμα:Qn:
Synonyms: CD27 CD3 CD45RA CD8 NFr Κύτταρα Κύτταρα.CD27 Κύτταρα.CD27- Κύτταρα.CD27+CD45RA- Κύτταρα.CD27+CD45RA+ Κύτταρα.CD27-CD45RA- Κύτταρα.CD27-CD45RA+ Κύτταρα.CD3 Κύτταρα.CD3+CD8+
es-ES Spanish (Spain) Células CD27+CD45RA-/Células CD3+CD8+:Fracción numérica:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cells.CD27 + CD45RA- / 100 Cells.CD3 + CD8 +:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
fr-FR French (France) CD27+CD45RA-/100 cellules CD3+CD8+:Fraction de nombres:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Cellule.CD27+CD45RA-/Cellule.CD3+CD8+:NFr:Pt:Sangue:Qn:
Synonyms: Cellule CD27 Cellule CD27- Cellule CD27+CD45RA- Cellule CD27+CD45RA+ Cellule CD27-CD45RA- Cellule CD27-CD45RA+ Cellule CD3 Cellule CD3+CD8+ Cellule CD3+CD8+ (cellule soppressore T8) Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) cellen.CD27+CD45RA-/cellen.CD3+CD8+:getalsfractie:moment:bloed:kwantitatief:
zh-CN Chinese (China) 细胞.CD27+CD45RA-/细胞.CD3+CD8+:计数型分数:时间点:全血:定量型:
Synonyms: CD27细胞 CD3+CD8+细胞 CD3细胞 CD45RA Leu18 Leu-18 Leu2 Leu-2 Leu4;Leu-4;T3 S152 T14 T8 T-8 Tsuppressor 发现于 抑制性 T-细胞/细胞毒性 T-细胞、一些 NK 细胞之上。与一些成熟 T-细胞肿瘤和大颗粒淋巴细胞增多症相关 发现于原态辅助 T-细胞、B-细胞以及粒细胞之上。与一些 T-细胞淋巴瘤和一些成熟 B-细胞淋巴瘤相关。 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抑制性 T 细胞 抑制性 T-细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80703-2