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Part Descriptions

LP100021-7   Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively. Source: Regenstrief Help

LP200619-7   Cells.CD27+CD45RA-
CD27 and CD45RA are both lymphocyte cell surface markers that can be used to classify T-cells into various subsets. Expression of CD27 is characteristic of naive T-cells and some subsets of memory T-cells, while lack of CD27 is characteristic of effector T-cells. PMID: 19454729. CD45RA is characteristic of resting or naive T-cells. Cells expressing both CD27+CD45RA+ are undifferentiated (naive), CD27+CD45RA- T-cells are at an early stage of differentiation and exhibit characteristics of memory T cells, whereas CD27-CD45RA- T-cells are highly differentiated and have characteristics of both memory and effector T-cells. PMID: 12023349 PMID: 21788446 Source: Regenstrief LOINC

LP17729-2   CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

LP20086-2   CD45RA
Found on Naive helper T-cells, B-cells and Granulocytes
Associated with some T-cell lymphomas and some mature B-cell lymphomas Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Cells.CD27+CD45RA-/Cells.CD3+CD8+:NFr:Pt:Bld:Qn:
Long Common Name
CD27+CD45RA- cells/CD3+CD8+ (T8 suppressor cells) cells in Blood
Short Name
CD27+CD45RA- cells/CD3+CD8+ Cll NFr Bld
Display Name
CD27+CD45RA- cells/CD3+CD8+ (T8 suppressor cells) cells (Bld)
Consumer Name Alpha Get Info
CD27+CD45RA- cells/CD3+CD8+ (T8 Suppressor Cells) Cells, Blood

Part Model Get Info

  • Component
    Cells.CD27+CD45RA-/Cells.CD3+CD8+
    LP445097-1
    • Analyte
      Cells.CD27+CD45RA-/Cells.CD3+CD8+
      LP445097-1
      • Component Numerator
        Cells.CD27+CD45RA-
        LP200619-7
        • Component Numerator Core
          Cells.CD27+CD45RA-
          LP200619-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Cells.CD3+CD8+
        LP100021-7
        • Component Denominator Core
          Cells.CD3+CD8+
          LP100021-7
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    NFr
    LP6838-9
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
80720-6T-cell naive and memory and effector (CD27 and CD45RA) subsets panel - Blood

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Buňky.CD27+CD45RA-/100 buněk.CD3+CD8+:Početní podíl:Časový bod:Krev:Kvantitativní:
el-GRGreek (Greece)Κύτταρα.CD27+CD45RA-/Κύτταρα.CD3+CD8+:NFr:Pt:Αίμα:Qn:
Synonyms: CD27 CD3 CD8 CELLMARK NFr Pt Qn Αίμα Κύτταρα Κύτταρα.CD27 Κύτταρα.CD27- Κύτταρα.CD27+CD45RA- Κύτταρα.CD27+CD45RA+ Κύτταρα.CD27-CD45RA- Κύτταρα.CD27-CD45RA+ Κύτταρα.CD3 Κύτταρα.CD3+CD8+
es-ESSpanish (Spain)Células CD27+CD45RA-/Células CD3+CD8+:Fracción numérica:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Cells.CD27 + CD45RA- / 100 Cells.CD3 + CD8 +:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
fr-FRFrench (France)CD27+CD45RA-/CD3+CD8+:Fraction de nombres:Ponctuel:Sang:Numérique:
it-ITItalian (Italy)Cellule.CD27+CD45RA-/Cellule.CD3+CD8+:NFr:Pt:Sangue:Qn:
Synonyms: Cellule CD27 Cellule CD27- Cellule CD27+CD45RA- Cellule CD27+CD45RA+ Cellule CD27-CD45RA- Cellule CD27-CD45RA+ Cellule CD3 Cellule CD3+CD8+ Cellule CD3+CD8+ (cellule soppressore T8) Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
nl-NLDutch (Netherlands)cellen.CD27+CD45RA-/cellen.CD3+CD8+:getalsfractie:moment:bloed:kwantitatief:
pl-PLPolish (Poland)Komórki.CD27+CD45RA-/komórki CD3+ CD8+:frakcja liczbowa:punkt w czasie:krew:ilościowy:
Synonyms: CD27 CD8 Komórki CD27 Komórki CD27+CD45RA+ Komórki CD27-CD45RA- Komórki CD27-CD45RA+ Komórki CD3+CD8+
zh-CNChinese (China)细胞.CD27+CD45RA-/细胞.CD3+CD8+:计数型分数:时间点:全血:定量型:
Synonyms: CD27细胞 CD3+CD8+细胞 CD3细胞 CD45RA Leu18 Leu-18 Leu2 Leu-2 Leu4;Leu-4;T3 S152 T14 T8 T-8 Tsuppressor 发现于 抑制性 T-细胞/细胞毒性 T-细胞、一些 NK 细胞之上。与一些成熟 T-细胞肿瘤和大颗粒淋巴细胞增多症相关 发现于原态辅助 T-细胞、B-细胞以及粒细胞之上。与一些 T-细胞淋巴瘤和一些成熟 B-细胞淋巴瘤相关。 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抑制性 T 细胞 抑制性 T-细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80703-2