80826-1
Zika virus envelope E gene [Presence] in Cerebral spinal fluid by NAA with probe detection
Active
Term Description
Per the Centers for Disease Control and Prevention's Trioplex Real-time RT-PCR Assay protocol, acceptable specimens for Zika testing are serum (not plasma), cerebrospinal fluid, urine, and amniotic fluid, and the probe target is the Zika virus envelope (E) gene.
Source: Regenstrief LOINC
Part Description
LP208630-6 Zika virus envelope (E) gene
Zika virus (ZIKV) is an arthropod-borne virus classified in the Flavivirus genus within the Falviviridae family 1. Flaviviruses include yellow fever virus, dengue virus, West Nile virus, St. Louis encephalitis virus and the Japanese encephalitis viruses. The genome of Flaviviruses is a single positive-strand RNA that is translated to produce a polyprotein that upon cleavage produces several proteins including the two major structural proteins (E and M). The "envelope E gene" and the "envelope M gene" correspond to the viral RNA regions that encode the E protein and the M protein. The virus envelope consists of a lipid bilayer derived from the host cell and 180 copies of M and E proteins arranged as 90 anti-parallel homodimers. N-linked glycosylation of the E protein may play a significant role in the pathogenicity of the virus. Further functional studies are needed to prove this hypothesis. PMID: 27148186
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Zika virus envelope (E) gene
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- Zika E gene CSF Ql NAA+probe
- Display Name
- ZIKV E gene NAA+probe Ql (CSF)
- Consumer Name Alpha Get Info
- Zika virus E gene, Spinal fluid
Example Answer List: LL744-4
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
Detected | LA11882-0 | ||
Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
81154-7 | Dengue and Chikungunya and Zika virus panel by NAA with probe detection |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG32774-8 | Zika virus |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Zika-Virus envelope (E)-Gen: Synonyms: Zerebrospinalflüssigkeit |
es-ES | Spanish (Spain) | Gen de la envoltura del virus Zika (E): |
es-MX | Spanish (Mexico) | Gen de la envoltura (E) del virus del Zika: |
fr-FR | French (France) | Zika virus enveloppe gène E: |
it-IT | Italian (Italy) | Zika virus, gene dell'involucro E: Synonyms: Gene dell''involucro E del virus Zika Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus Zika |
nl-NL | Dutch (Netherlands) | zikavirus envelop (E) gen: Synonyms: probe.amp.tar Zika-virus |
zh-CN | Chinese (China) | 寨卡病毒包膜 (E) 基因: Synonyms: CSF CSF; |
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