Version 2.80

Term Description

The projected heparin concentration is the amount of heparin required to increase the patient's ACT to the clinician specified target value and is based the target ACT and the slope of the patient's response to known amounts of heparin. This term was created for, but is not limited in use to, the submitter's Medtronic Heparin Dose Response test kit.

Part Description

LP206571-4   Projected heparin concentration to reach target ACT
The projected heparin dose response test is a point-of-care test performed on fresh whole blood (no citrate added) to assess patient's individual response to heparin. The test measures the baseline (no heparin) activated clotting time, and the activated clotting times on the same blood to which 2 different concentrations of unfractionated heparin is added. From these measurements a projected dose response is calculated. This test is used in the cardiac operating room where patients are anticoagulated with high (3 to 5 units heparin/mL of blood) levels of unfractionated heparin. The effect of this level of heparin anticoagulation is measured every 20 to 30 minutes while the patient is on cardiopulmonary bypass. The heparin dose response is used to determine the appropriate amount of heparin needed to increase the patient's activated clotting time to the target level used by the hospital. The heparin dose response test is typically performed once at the beginning of the surgical procedure before the patient is placed on bypass. Once the patient is heparinized and placed on bypass the activated clotting time and the heparin concentration (whole blood heparin assay) are determined in the operating room every 20 to 30 minutes during the procedure. Heparin administered to patients in the cardiac OR is unfractionated, not low molecular weight. The amount given greatly exceeds the amount that could be monitored by the APTT. In this setting the most important concern is that the patient receive the appropriate amount in order to reach and maintain the required anticoagulant (thrombin inhibiting) protection. Source: Regenstrief LOINC

Fully-Specified Name

Component
Projected heparin concentration to reach target ACT
Property
ACnc
Time
Pt
System
Bld
Scale
Qn
Method
Calculated

Additional Names

Long Common Name
Projected heparin concentration to reach target ACT [Units/volume] in Blood by calculation
Short Name
Proj heparin conc Bld Calc-aCnc
Display Name
Projected heparin concentration to reach target ACT Calc Qn (Bld)
Consumer Name Alpha Get Info
Projected Heparin Concentration to Reach Target ACT, Blood

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.68 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
81281-8 Heparin dose response panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Προβλεπόμενη συγκέντρωση ηπαρίνης για την επίτευξη του ενεργοποιημένου χρόνου πήξης-στόχου:ACnc:Pt:Αίμα:Qn:Υπολογιζόμενο
Synonyms: ACnc Ηπαρίνη Προβλεπόμενη συγκέντρωση ηπαρίνης για την επίτευξη του ενεργοποιημένου χρόνου πήξης-στόχου
es-ES Spanish (Spain) Concentración de heparina prevista para alcanzar el objetivo ACT:Concentración arbitraria:Punto temporal:Sangre:Qn:Calculado
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Concentración de heparina proyectada para alcanzar el ACT objetivo:Concentración arbitraria:Punto temporal:Sangre:Cuantitativo:Calculado
fr-FR French (France) Héparine concentration pour TCA cible:Arbitraire/Volume:Ponctuel:Sang:Numérique:Résultat calculé
fr-CA French (Canada) Héparine concentration pour TCA cible:Concentration arbitraire:Temps ponctuel:Sang:Quantitatif:Calculé
it-IT Italian (Italy) Concentrazione di eparina prevista per raggiungere il target ACT:ACnc:Pt:Sangue:Qn:Calcolato
Synonyms: Concentrazione Arbitraria Punto nel tempo (episodio) Sangue Studio di coagulazione
zh-CN Chinese (China) 达到活化凝血时间的预计肝素浓度:任意型浓度:时间点:全血:定量型:计算法
Synonyms: 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 肝制凝素;肝磷脂 血;血液 计算;计算型方法 达到活化凝血时间（ACT、激活凝血时间、激活全血凝固时间）的预计（计划、推算、预测）肝素浓度;达到活化凝血时间所需的预计肝素浓度

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80893-1