80893-1

Projected heparin concentration to reach target ACT [Units/volume] in Blood by calculation

Active

Term Description

The projected heparin concentration is the amount of heparin required to increase the patient's ACT to the clinician specified target value and is based the target ACT and the slope of the patient's response to known amounts of heparin. This term was created for, but is not limited in use to, the submitter's Medtronic Heparin Dose Response test kit.

Part Description

LP206571-4 Projected heparin concentration to reach target ACT
The projected heparin dose response test is a point-of-care test performed on fresh whole blood (no citrate added) to assess patient's individual response to heparin. The test measures the baseline (no heparin) activated clotting time, and the activated clotting times on the same blood to which 2 different concentrations of unfractionated heparin is added. From these measurements a projected dose response is calculated. This test is used in the cardiac operating room where patients are anticoagulated with high (3 to 5 units heparin/mL of blood) levels of unfractionated heparin. The effect of this level of heparin anticoagulation is measured every 20 to 30 minutes while the patient is on cardiopulmonary bypass. The heparin dose response is used to determine the appropriate amount of heparin needed to increase the patient's activated clotting time to the target level used by the hospital. The heparin dose response test is typically performed once at the beginning of the surgical procedure before the patient is placed on bypass. Once the patient is heparinized and placed on bypass the activated clotting time and the heparin concentration (whole blood heparin assay) are determined in the operating room every 20 to 30 minutes during the procedure. Heparin administered to patients in the cardiac OR is unfractionated, not low molecular weight. The amount given greatly exceeds the amount that could be monitored by the APTT. In this setting the most important concern is that the patient receive the appropriate amount in order to reach and maintain the required anticoagulant (thrombin inhibiting) protection. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Projected heparin concentration to reach target ACT:ACnc:Pt:Bld:Qn:Calculated
Long Common Name: Projected heparin concentration to reach target ACT [Units/volume] in Blood by calculation
Short Name: Proj heparin conc Bld Calc-aCnc
Display Name: Projected heparin concentration to reach target ACT Calc Qn (Bld)
Consumer Name Alpha Get Info: Projected Heparin Concentration to Reach Target ACT, Blood

Part Model Get Info

Component
Projected heparin concentration to reach target ACT
LP206571-4
- Analyte
  Projected heparin concentration to reach target ACT
  LP206571-4
  - Component Numerator
    Projected heparin concentration to reach target ACT
    LP206571-4
    - Component Numerator Core
      Projected heparin concentration to reach target ACT
      LP206571-4
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Calculated
LP6165-7

Basic Attributes

Class: COAG
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.68 (MIN)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
81281-8	Heparin dose response panel - Blood

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Heparin předpokládaná koncentrace k dosažení cílové ACT:Arbitrární koncentrace:Časový bod:Krev:Kvantitativní:Vypočteno
el-GR	Greek (Greece)	Προβλεπόμενη συγκέντρωση ηπαρίνης για την επίτευξη του ενεργοποιημένου χρόνου πήξης-στόχου:ACnc:Pt:Αίμα:Qn:Υπολογιζόμενο Synonyms: ACnc COAG Pt Qn Αίμα Ηπαρίνη Προβλεπόμενη συγκέντρωση ηπαρίνης για την επίτευξη του ενεργοποιημένου χρόνου πήξης-στόχου Υπολογιζόμενο
es-ES	Spanish (Spain)	Concentración de heparina prevista para alcanzar el objetivo ACT:Concentración arbitraria:Punto temporal:Sangre:Qn:Calculado Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Concentración de heparina proyectada para alcanzar el ACT objetivo:Concentración arbitraria:Punto temporal:Sangre:Cuantitativo:Calculado
fr-FR	French (France)	Héparine concentration pour TCA cible:Arbitraire/Volume:Ponctuel:Sang:Numérique:Résultat calculé
fr-CA	French (Canada)	Héparine concentration pour TCA cible:Concentration arbitraire:Temps ponctuel:Sang:Quantitatif:Calculé
it-IT	Italian (Italy)	Concentrazione di eparina prevista per raggiungere il target ACT:ACnc:Pt:Sangue:Qn:Calcolato Synonyms: Concentrazione Arbitraria Punto nel tempo (episodio) Sangue Studio di coagulazione
zh-CN	Chinese (China)	达到活化凝血时间的预计肝素浓度:任意型浓度:时间点:全血:定量型:计算法 Synonyms: 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间肝制凝素;肝磷脂血;血液计算;计算型方法达到活化凝血时间（ACT、激活凝血时间、激活全血凝固时间）的预计（计划、推算、预测）肝素浓度;达到活化凝血时间所需的预计肝素浓度

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.