81101-8
Leptospira interrogans sv Copenhageni Ab [Titer] in Serum by Agglutination
Active
Part Descriptions
LP19907-2 Leptospira interrogans serovar Copenhageni
Leptospira is a flexible, spiral-shaped, Gram-negative spirochete with internal flagella. Leptospira interrogans has many serovars based on cell surface antigens. Most leptospirosis infections initially present with an acute onset of fever, headache and muscle pain, which symptoms last about a week. The three organ systems most frequently involved with more significant illness are the central nervous system, kidneys, and liver, and jaundice occurs with severe infections. With the appearance of antileptospiral antibodies, the acute phase of the disease subsides and leptospires can no longer be isolated from the blood. The disease is usually biphasic, with the acute phase followed by an immune phase, which occurs after an asymptomatic period of several days. The immune phase is associated with fever and central nervous system involvement, specifically meningitis. Leptospires appear in the urine during this phase and are shed for various periods depending on the host. Severe leptospirosis is associated with progressive impairment of hepatic and renal function, and renal failure is the most common cause of death.
Leptospirosis is a worldwide zoonosis with a variety of animal hosts. The primary reservoir is wild animals such as rodents, which can shed leptospires throughout their lifetimes. Domestic animals are also an important source of human infections. The disease is more widespread in tropical countries. Direct or indirect contact with urine containing virulent leptospires is the major means by which leptospirosis is transmitted.
Leptospira species, which include L. interrogans, L. autumnalis, L. borgpetersenii, and L. weili are further divided into more than 200 serotypes based on their antigenic composition. The more severe form of leptospirosis is frequently associated with the icterohaemorrhagiae serotype and is often referred to as Weil's disease. [NCBI Books: NBK8451]
Source: Regenstrief LOINC, NCBI Books: NBK8451
LP19907-2 Leptospira interrogans serovar Copenhageni
Different strains of Leptospira have different degrees of virulence. L. interrogans serovar Copenhageni frequently results in life-threatening infections that are associated with jaundice, kidney injury and hemorrhage. The host of the Copenhageni serovar is Rattus norvegicus, which is also the host of other strains of Leptospira that are less virulent. PMID: 26518696 The majority of human leptospirosis infections in Brazil are due to L. interrogans serovar Copenhageni. PMID: 24098496
Source: Regenstrief LOINC, PMID: 24098496
Fully-Specified Name
- Component
- Leptospira interrogans serovar Copenhageni Ab
- Property
- Titr
- Time
- Pt
- System
- Ser
- Scale
- SemiQn
- Method
- Aggl
Additional Names
- Short Name
- L inter Copen Ab Titr Ser Aggl
- Display Name
- L. interrogans sv Copenhageni Ab Aggl (S) [Titer]
- Consumer Name Alpha Get Info
- Leptospira interrogans serovar Copenhageni antibody, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG41636-8 | Leptospira |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Leptospira interrogans Serovar Copenhageni Ak: |
| es-ES | Spanish (Spain) | Leptospira interrogans serotipo Copenhageni Anticuerpos: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Leptospira interrogans serovar Copenhageni Ab: |
| fr-FR | French (France) | Leptospira interrogans serovar Copenhageni Ac: |
| fr-CA | French (Canada) | Leptospira interrogans serovar Copenhageni , Ac: |
| it-IT | Italian (Italy) | Leptospira interrogans sierotipo Copenhageni Ab: Synonyms: Agglutinazione anticorpo Leptospira interrogans serovar Copenhageni Microbiologia Punto nel tempo (episodio) Siero Titolo |
| nl-NL | Dutch (Netherlands) | Leptospira interrogans serotype Copenhageni As: Synonyms: antistof; |
| zh-CN | Chinese (China) | 致病性钩端螺旋体 Copenhageni 血清型变种 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
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