81110-9
Leptospira weilii serovar Topaz Ab [Titer] in Serum by Agglutination
Active
Part Descriptions
LP171712-5 Leptospira weilii serovar Topaz
Leptospira is a flexible, spiral-shaped, Gram-negative spirochete with internal flagella. Leptospira interrogans has many serovars based on cell surface antigens. Most leptospirosis infections initially present with an acute onset of fever, headache and muscle pain, which symptoms last about a week. The three organ systems most frequently involved with more significant illness are the central nervous system, kidneys, and liver, and jaundice occurs with severe infections. With the appearance of antileptospiral antibodies, the acute phase of the disease subsides and leptospires can no longer be isolated from the blood. The disease is usually biphasic, with the acute phase followed by an immune phase, which occurs after an asymptomatic period of several days. The immune phase is associated with fever and central nervous system involvement, specifically meningitis. Leptospires appear in the urine during this phase and are shed for various periods depending on the host. Severe leptospirosis is associated with progressive impairment of hepatic and renal function, and renal failure is the most common cause of death.
Leptospirosis is a worldwide zoonosis with a variety of animal hosts. The primary reservoir is wild animals such as rodents, which can shed leptospires throughout their lifetimes. Domestic animals are also an important source of human infections. The disease is more widespread in tropical countries. Direct or indirect contact with urine containing virulent leptospires is the major means by which leptospirosis is transmitted.
Leptospira species, which include L. interrogans, L. autumnalis, L. borgpetersenii, and L. weili are further divided into more than 200 serotypes based on their antigenic composition. The more severe form of leptospirosis is frequently associated with the icterohaemorrhagiae serotype and is often referred to as Weil's disease. [NCBI Books: NBK8451]
Source: Regenstrief LOINC, NCBI Books: NBK8451
LP171712-5 Leptospira weilii serovar Topaz
Leptospira weilii serovar Topaz was first isolated from a human in Australia in 1990, and since then, Topaz has been isolated from cattle and bandicoots. Although the organism has not been isolated from kangaroos, there is serological evidence for kangaroo infection. Human leptospirosis cases due to serovar Topaz have been increasing since 2003. [https://www.health.qld.gov.au/qhcss/qhss/lepto/documents/topaz.pdf]
Source: Mater Hospital and Health Services, Queensland Department of Health: Leptospira weilii serovar Topaz
Fully-Specified Name
- Component
- Leptospira weilii serovar Topaz Ab
- Property
- Titr
- Time
- Pt
- System
- Ser
- Scale
- SemiQn
- Method
- Aggl
Additional Names
- Long Common Name
- Leptospira weilii serovar Topaz Ab [Titer] in Serum by Agglutination
- Short Name
- L weilii Topaz Ab Titr Ser Aggl
- Display Name
- L. weilii serovar Topaz Ab Aggl (S) [Titer]
- Consumer Name Alpha Get Info
- Leptospira weilii serovar Topaz antibody, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG41636-8 | Leptospira |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Leptospira weilii Serovar Topaz Ak: |
es-ES | Spanish (Spain) | Leptospira weilii serovar Topaz Anticuerpos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Leptospira weilii serovar Topaz Ab: |
fr-FR | French (France) | Leptospira weilii serovar Topaz Ac: |
it-IT | Italian (Italy) | Leptospira weilii sierotipo Topaz Ab: Synonyms: Agglutinazione anticorpo Microbiologia Punto nel tempo (episodio) Siero Titolo |
nl-NL | Dutch (Netherlands) | Leptospira weilii serovar Topaz As: Synonyms: antistof; |
zh-CN | Chinese (China) | 韦氏钩端螺旋体 Topaz 血清型变种 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
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