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Term Description

This assay detects hepatitis C core antigen and antibodies to the core antigen and does not distinguish between the two. The hepatitis C core protein forms the viral capsid. This term was created for, but is not limited in use to, the submitter's Biorad Monolisa HCV Ag-Ab ULTRA assay.

Part Description

LP207929-3   Hepatitis C virus core Ab+Ag
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LOINC Names Get Info

Fully-Specified Name
Hepatitis C virus core Ab+Ag:PrThr:Pt:Ser:Ord:
Long Common Name
Hepatitis C virus core Ab+Ag [Presence] in Serum
Short Name
HCV core Ab+Ag Ser Ql
Display Name
HCV core Ab+Ag Ql (S)
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) Core Ab+Ag, Blood

Part Model Get Info

  • Component
    Hepatitis C virus core Ab+Ag
    LP207929-3
    • Analyte
      Hepatitis C virus core Ab+Ag
      LP207929-3
      • Component Numerator
        Hepatitis C virus core Ab+Ag
        LP207929-3
        • Component Numerator Core
          Hepatitis C virus core Ab+Ag
          LP207929-3
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    NULL
     

Example Answer List: LL744-4

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
DetectedLA11882-0
Not detectedLA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.56 (MIN)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG32754-0Hepatitis C virus

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus hepatitidy C core Ab+Ag:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:
el-GRGreek (Greece)Αντισώματα+Αντιγόνα πυρήνα ιού ηπατίτιδας C:PrThr:Pt:Ορός:Ord:
Synonyms: C MICRO Ord PrThr Pt Αντισώματα+Αντιγόνα πυρήνα ιού ηπατίτιδας C Ιός Ιός ηπατίτιδας C Ορός Πυρήνας ιού ηπατίτιδας C
es-ESSpanish (Spain)Anticuerpo + Antígeno core del vitus de la Hepatitis C:PrThr:Punto temporal:Suero:Ord:
es-MXSpanish (Mexico)Núcleo del virus de la hepatitis C Ab + Ag:Presencia o umbral:Punto temporal:Suero:Ordinal:
fr-FRFrench (France)Hépatite C virus core Ac+Ag:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
it-ITItalian (Italy)Epatite C virus, core Ab+Ag:PrThr:Pt:Siero:Ord:
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Virus dell''epatite C Virus dell''epatite C core Virus dell''epatite C core Ab+Ag
nl-NLDutch (Netherlands)Hepatitis C-virus core Ab + Ag:aanwezigheid:moment:serum:ordinaal:
pl-PLPolish (Poland)Ab do rdzenia HCV + Ag rdzeniowy:granica wykrywalności:punkt w czasie:surowica:uporządkowany:
Synonyms: Przeciwciała przeciw rdzeniowi wirusa zapalenia wątroby typu C+antygen rdzeniowy
zh-CNChinese (China)丙型肝炎病毒核心抗体+抗原:存在情况或阈值:时间点:血清:序数型:
Synonyms: C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）核心 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）核心抗体+抗原（Ab+Ag） 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 肝

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81116-6