81718-9
Deprecated Ganglioside GM1 IgG+IgM Ab [Presence] in Serum by Immunoblot
Deprecated
Status Information
- Status
- DEPRECATED
- Reason
- Duplicate
- Comment
- Created with Method "IB" but upon further review found to be "IA", which makes this term a duplicate.
Map-To | Long Common Name | Mapping Guidance |
---|---|---|
63244-8 | Ganglioside GM1 IgG+IgM Ab [Presence] in Serum by Immunoassay |
Part Descriptions
LP36423-9 Ganglioside GM1
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559
Source: Regenstrief LOINC, PMID: 2121455
LP222219-0 Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Ganglioside GM1 Ab.IgG+IgM
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IB
Additional Names
- Short Name
- Deprecated GM1 Gangl IgG+IgM Ser Ql IB
- Display Name
- Ganglioside GM1 IgG+IgM IB Ql (S)
- Consumer Name Alpha Get Info
- Ganglioside GM1 IgG+IgM, Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.58
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG12484-8 | Ganglioside GM1 Ab.IgG+IgM| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Gangliósido GM1 IgG+IgM: |
es-MX | Spanish (Mexico) | Gangliósido GM1 Ab.IgG + IgM: |
et-EE | Estonian (Estonia) | Gangliosiid GM1 antikehad.IgG+IgM: Synonyms: Immuunglobuliin G Immuunglobuliin M Järgarvuline Juhuslik Seerum |
fr-CA | French (Canada) | Ganglioside GM1, IgG+IgM: |
fr-BE | French (Belgium) | Ganglioside GM1 Anticorps.IgG+IgM: Synonyms: Anticorps |
it-IT | Italian (Italy) | Ganglioside GM1 Ab.IgG+IgM: Synonyms: anticorpi IgG anticorpi IgG e IgM Anticorpi IgG+IgM anticorpo Immunoblot (IB) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | ganglioside GM1 As.IgG + IgM: Synonyms: antistof; |
ru-RU | Russian (Russian Federation) | Ганглиозид GM1 Ат.IgG+IgM: Synonyms: Антитело Иммуноблот (ИБ) Порядковый Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Gangliozid GM1 Ab.IgG+IgM: Synonyms: Ak Ak.IgG Ak.IgG+IgM Mevcut |
zh-CN | Chinese (China) | 神经节苷脂 GM1 抗体.IgG+IgM: Synonyms: Ab.IgG; |
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Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright