Version 2.78

Status Information

Status
DEPRECATED
Reason
Duplicate
Comment
Created with Method "IB" but upon further review found to be "IA", which makes this term a duplicate.
Map-To Long Common Name Mapping Guidance
63337-0 SCL-70 extractable nuclear Ab [Presence] in Cerebral spinal fluid by Immunoassay

Part Description

LP16758-2   SCL-70 extractable nuclear
Topoisomerase I (also known as Scl-70) is a nuclear enzyme that plays a role in releasing tension that is introduced in double-stranded DNA during DNA replication by transiently cleaving and rejoining one strand of the DNA duplex. Anti-Scl-70 autoantibodies are a marker of systemic sclerosis as well as other autoimmune diseases, including systemic lupus erythematosus (SLE). In patients with systemic sclerosis, anti-SCL-70 may be associated with more severe disease, and in patients with SLE, anti-SCL-70 suggests an increased risk of pulmonary hypertension and renal involvement. In general, anti-SCL-70 antibody status may help with diagnosis, treatment planning and prognosis in patients with connective tissue disease. PMID: 11229469 Source: Regenstrief LOINC, PMID: 11229469

Fully-Specified Name

Component
SCL-70 extractable nuclear Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IB

Additional Names

Short Name
Deprecated ENA Scl70 Ab CSF Ql IB
Display Name
SCL-70 extractable nuclear Ab IB Ql (CSF)
Consumer Name Alpha Get Info
SCL-70 extractable nuclear antibody, Spinal fluid

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.58
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG26773-8 SCL-70 extractable nuclear Ab|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Antígeno nuclear extraíble SCL-70 Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunoblot (IB)
es-MX Spanish (Mexico) Ab nuclear extraíble SCL-70:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunotransferencia
fr-CA French (Canada) SCL-70 nucléaire soluble, Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunoblot
fr-BE French (Belgium) SCL-70 nucléaire soluble Ac:PrThr:Temps ponctuel:LCR:Ordinal:Immunoblot
Synonyms: Anticorps
it-IT Italian (Italy) Nucleare estraibile SCL-70 Ab:PrThr:Pt:LCS:Ord:IB
Synonyms: anticorpo ENA Immunoblot (IB) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) SCL-70 extraheerbare nucleaire As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoblotting
Synonyms: antistof; antilichaam IB
pl-PL Polish (Poland) SCL-70 rozpuszczalny jądrowy Ab:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:immunoblotting
Synonyms: Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała przeciwjądrowe SCL-70 rozpuszczalny jądrowy
ru-RU Russian (Russian Federation) SCL-70 экстрагируемый ядерный Ат:PrThr:ТчкВрм:ЦСЖ:Пор:ИБ
Synonyms: Антитело Иммуноблот (ИБ) Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) SCL-70 özütlenebilir nükleer Ab:MevcEşik:Zmlı:BOS:Srl:IB
Synonyms: Ak Çekirdek Mevcut
zh-CN Chinese (China) SCL-70 可提取性核 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫印迹法
Synonyms: Ab;自身抗体 ANA CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 ENA Ab ENA SCL-70 Ab ENA SCL-70 抗体 ENA SCL-70;SCL-70 可提取性核 Ag;SCL-70 可提取性核抗原;可提取性核抗原 SCL-70;皮硬化症 Ab;皮硬化症抗体;硬皮病 Ab;硬皮病抗体;硬皮症 Ab;硬皮症抗体 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原（Extractable Nuclear Antigen，ENA）;可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 NA SCL-70 可提取性核 Ab SCL-70 可提取性核 Ag Ab SCL-70 可提取性核抗原抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 可提取性核 Ab 可提取性核 Ag 之 Ab 可提取性核抗原 SCL-70 Ab 可提取性核抗原 SCL-70 抗体 可提取性核抗原之抗体 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 抗 ENA 抗可提取性核 Ag 抗可提取性核抗原 抗核 Ab 抗核抗体 抗核抗体（Antinuclear antibody，ANA） 时刻;随机;随意;瞬间 核;胞核 皮硬化症 硬皮病 硬皮病（Scleroderma，SCL） 硬皮症 细胞核 Ab 胞核 Ab 胞核抗体 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81739-5