Version 2.78

Term Description

This assay detects the presence of nucleic acid sequences from the Varicella zoster virus DNA in cerebrospinal fluid (CSF) using PCR and non-probe based detection methods, such as melt curve analysis. This term was created for, but is not limited in use to, BioFire's FilmArray Meningitis/Encephalitis Panel, which is intended for the detection and identification of nucleic acids from multiple bacteria, viruses, and yeast directly from CSF obtained via lumbar puncture from individuals with signs and/or symptoms of meningitis and/or encephalitis.
Source: Regenstrief LOINC

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus DNA
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
Non-probe.amp.tar

Additional Names

Short Name
VZV DNA CSF Ql NAA+non-probe
Display Name
VZV DNA NAA+non-probe Ql (CSF)
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox), Spinal fluid

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
4250

Member of these Panels

LOINC Long Common Name
82180-1 Meningitis+Encephalitis pathogens panel - Cerebral spinal fluid by NAA with non-probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Varicella-Zoster-Virus DNA:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde
Synonyms: Human alphaherpesvirus 3; VZV; Zerebrospinalflüssigkeit
es-ES Spanish (Spain) Virus Varicella zoster ADN:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Amplificación del objetivo no basado en sonda
es-MX Spanish (Mexico) ADN del virus de la varicela zóster:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-CA French (Canada) Virus varicelle-zona, ADN:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Non-sonde.amplification de cible
fr-FR French (France) Varicelle zona virus ADN:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Non-PCR amplification de cible
it-IT Italian (Italy) Varicella zoster, virus DNA:PrThr:Pt:LCS:Ord:Non-sonda.amp.tar
Synonyms: Amplificazione target non basata su sonda Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus della varicella zoster
uk-UA Ukrainian (Ukraine) ДНК вірусу Varicella Zoster:Наявність або Поріг:МоментЧасу:Спинномозкова рідина:Порядково:Детекція без зонда.цільова аміпліфікація НК
Synonyms: 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; Cerebral spinal fluid; Cerebrospinal Fl; Chicken pox; Chicken pox virus; Chickenpox; Deoxyribonucleic acid; DNA NUCLEIC ACID PROBE; DNA probe; Herpes zoster; HHV-3; Human herpesvirus 3; ID; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Microbiology; NAA+non-probe; NAA+probe; NAAT; NASBA; Neuro; Neurology; Nucleic acid sequence based analysis; Ordinal; PCR; Point in time; Polymerase chain reaction; PR; Probe amp; Probe with ampification; Probe with target amplification; QBR; QL; Qual; Qualitative; Random; Screen; SDA; Shingles; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid; Strand Displacement Amplification; TMA; Transcription mediated amplification; VZ; VZV; Zoster
zh-CN Chinese (China) 水痘带状疱疹病毒 DNA:存在情况或阈值:时间点:脑脊液:序数型:非探针法.基因扩增.靶向
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 HHV-3 DNA HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 VZV DNA 人类疱疹病毒 3 型 DNA 人类疱疹病毒 III 型 DNA 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 水痘病毒 DNA 经过扩增的 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 脱氧核糖核酸探针

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CodeSystem lookup
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