82399-7
Ganglioside GD2 IgG Ab [Presence] in Serum by Line blot
Active
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Part Descriptions
LP99610-5 Ganglioside GD2
Anti-ganglioside autoantibodies are one marker of multiple sclerosis (MS). In one study, about 30% of patients with MS had anti-GD2-like IgM autoantibodies, and some of those also had antibodies to GD1a and/or GD3. Presence of anti-GD2-like antibodies was associated with significantly more neurological disability compared to patients with MS that did not have anti-GD2-like antibodies. PMID: 16764343
Source: Regenstrief LOINC, PMID: 16764343
LP222219-0 Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Ganglioside GD2 Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- GD2 Gangl IgG Ser Ql Line blot
- Display Name
- Ganglioside GD2 IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- Ganglioside GD2 IgG antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
82455-7 | Ganglioside Ab panel - Serum |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Gangliosido GD2 IgG: |
es-MX | Spanish (Mexico) | Gangliósido GD2 Ab.IgG: |
fr-CA | French (Canada) | Ganglioside GD2, IgG: |
fr-FR | French (France) | Ganglioside GD2 anticorps IgG: |
it-IT | Italian (Italy) | Ganglioside GD2 Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | ganglioside GD2 As.IgG: Synonyms: antistof; |
zh-CN | Chinese (China) | 神经节苷脂 GD2 抗体.IgG: Synonyms: Ab.IgG; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=82399-7
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright