82527-3
6-Beta naltrexol/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP220262-2 6-Beta naltrexol
Naltrexol has two forms: 6-beta naltrexol and 6-alpha naltrexol. 6-Beta naltrexol (6β-Naltrexol) is the major urinary metabolite of Naltrexone in man and has a significant pharmacological activity and a longer elimination half-life than the parent drug. PMID: 9248940 Naltrexone is an opioid antagonist used primarily in the management of alcohol dependence and opioid dependence. Relative to naltrexone, 6β-naltrexol has about half the affinity for the μ-opioid receptor, but is present at approximately 10-30-fold higher concentrations at steady state due to extensive first-pass metabolism of the parent drug.
Source: Regenstrief LOINC
, 6β-Naltrexol
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Creatinine
Fully-Specified Name
- Component
- 6-Beta naltrexol/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- 6-Beta naltrexol/Creatinine [Mass Ratio] in Urine
- Short Name
- 6-Beta naltrexol/Creat Ur
- Display Name
- 6-Beta naltrexol/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- 6-Beta naltrexol/Creatinine, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.58 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | 6-β ναλτρεξόλη/Κρεατινίνη: Synonyms: 6-β ναλτρεξόλη MRto Κρεατινίνη Ναλτρεξόλη |
es-ES | Spanish (Spain) | 6-beta naltrexol/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 6-Beta naltrexol / Creatinina: |
fr-FR | French (France) | 6-Bêta-naltréxol/créatinine: |
it-IT | Italian (Italy) | 6-beta naltrexolo/Creatinina: Synonyms: Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di Massa |
nl-NL | Dutch (Netherlands) | 6-bèta-naltrexol/creatinine: Synonyms: kreatinine |
zh-CN | Chinese (China) | 6-beta 纳曲醇/肌酐: Synonyms: 6-β纳曲醇; |
Example Units
Unit | Source |
---|---|
ng/g{creat} | Example UCUM Units |
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