82992-9
SUMO-activating enzyme subunit 1 IgG Ab [Presence] in Serum by Line blot
Active
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Part Description
LP230275-2 SUMO-activating enzyme subunit 1 Ab.IgG
Small ubiquitin-like modifier 1 (SUMO-1) is one of four enzymes in the SUMO family which plays a key role in posttranslational protein modification. SUMO-1 consists of the SUMO-1 activating enzyme A subunit (SAE1) and the SUMO-1 activating enzyme B subunit (SAE2), which have molecular weights of 40kD and 90kD, respectively. The SUMO family has been associated with diseases such as rheumatoid arthritis and primary biliary cirrhosis. SAE1 and SAE2 have been found in patients with dermatomyositis (DM) associated with widespread skin involvement, dysphagia, and interstitial pneumonia. Patients with DM without these specific associated symptoms are typically anti-SAE antibody negative. PMID: 17763420
Source: Regenstrief LOINC, PMID: 17763420
Fully-Specified Name
- Component
- SUMO-activating enzyme subunit 1 Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- SAE1 IgG Ser Ql Line blot
- Display Name
- SUMO-activating enzyme subunit 1 IgG Line blot Ql (S)
- Consumer Name Alpha Get Info
- SUMO-activating enzyme subunit 1 IgG antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: SAE-1 AK ql. |
es-ES | Spanish (Spain) | subunidad 1 de la enzima activadora de SUMO IgG: |
es-MX | Spanish (Mexico) | Subunidad de enzima activadora de SUMO 1 Ab.IgG: |
fr-FR | French (France) | SAE1 anticorps IgG: |
it-IT | Italian (Italy) | Enzima SUMO-attivante, subunità 1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Subunità 1 di enzima SUMO-attivante |
nl-NL | Dutch (Netherlands) | SUMO-activerend enzym subeenheid 1 As.IgG: Synonyms: antistof; |
zh-CN | Chinese (China) | SUMO-活化酶亚基 1 抗体.IgG: Synonyms: Ⅰ Ab.IgG; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=82992-9
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright