82998-6
Dense fine speckled 70 protein IgG Ab [Presence] in Serum or Plasma by Line blot
Active
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
Part Description
LP230331-3 Dense fine speckled 70 protein Ab.IgG
Antinuclear antibodies are essential to diagnose systemic autoimmune rheumatic diseases (SARDs) such as Lupus erythematosus and scleroderma. However, 20-30% of healthy people test positive for ANAs,half of which are dense fine speckled 70 protein (DFS70) antibodies. DFS70 antibodies have been found in patients with various chronic inflammatory diseases but no one disease in particular. It has been suggested that the best use for measuring DFS70 antibodies might be as a biomarker that excludes the diagnosis of SARD since DFS70 antibodies are more often found in patients without active SARD than with it. Antibody titers of DFS70 are highest in healthy young females and the titers decline as a person ages.( http://cli-online.com/featured-articles/anti-dfs70-antibodies-detection-and-significance/)
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Dense fine speckled 70 protein Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- DFS70 IgG SerPl Ql Line blot
- Display Name
- Dense fine speckled 70 protein IgG Line blot Ql
- Consumer Name Alpha Get Info
- Dense fine speckled 70 protein IgG antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG50952-7 | Dense fine speckled 70 protein Ab.IgG| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: DFS70-AK ql. |
es-ES | Spanish (Spain) | Proteína densa fina moteada 70 IgG: |
es-MX | Spanish (Mexico) | Ab.IgG de proteína 70 moteada fina y densa: |
fr-FR | French (France) | DFS70 anticorps IgG: |
it-IT | Italian (Italy) | Proteina 70 densa fine punteggiata Ab.IgG: Synonyms: anticorpi IgG anticorpo Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | dense fine speckled 70 protein As.IgG: Synonyms: antistof; |
zh-CN | Chinese (China) | 致密细斑 70 蛋白 抗体.IgG: Synonyms: Ab.IgG; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright