84925-7

PCA-2 Ab [Presence] in Serum by Immunofluorescence

Active

Term Description

Antineuronal antibodies against PCA-2 are detected and characterized based on immunofluorescence staining pattern on multiple neuronal, non-neuronal tissues, and transformed substrate cells.
Source: Regenstrief LOINC

Part Description

LP31708-8 Purkinje cell cytoplasmic type 2
Anti-PCA-2 (purkinje cell cytoplasmic antibody type 2) autoantibodies are important markers of neurological autoimmunity related to cancer. PCA-2 binds to cerebellar Purkinje somata and dendrites, neurons in internal granular layer and dentate nucleus, and neuronal elements in gut and kidney. Patients present with mixed subacute neurological diorders, including brainstem or limbic encephalitis, cerebellar ataxia, Lambert-Eaton myasthenic syndrome, and autonomic and motor neuropathy. Patients with symptoms of such disorders, especially those with known risk factors for cancer, will undergo testing for paraneoplastic antibodies, including PCA-2. Testing is also performed to monitor the immune response of seropositive patients in the course of cancer therapy. PMID: 10716248 Source: Regenstrief LOINC

Fully-Specified Name

Component: Purkinje cell cytoplasmic type 2 Ab
Property: PrThr
Time: Pt
System: Ser
Scale: Ord
Method: IF

Additional Names

Short Name: PCA-2 Ab Ser Ql IF
Display Name: PCA-2 Ab IF Ql (S)
Consumer Name Alpha Get Info: PCA-2 antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.73
Order vs. Observation: Both
Common Test Rank Get Info: 7771

Member of these Groups Get Info

LOINC Group	Group Name
LG51340-4	Purkinje cell cytoplasmic type 2 Ab\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
de-AT	German (Austria)	Synonyms: PCA-2 AK ql.
es-ES	Spanish (Spain)	Células de Purkinje tipo 2 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX	Spanish (Mexico)	Ab citoplasmático tipo 2 de células de Purkinje:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
fr-CA	French (Canada)	Cellules de Purkinje cytoplasmique type 2 , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-FR	French (France)	APCA-2 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
fr-BE	French (Belgium)	Cellules de Purkinje type 2 Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunofluorescence Synonyms: Anticorps
it-IT	Italian (Italy)	Cellule di Purkinje tipo 2 Ab:PrThr:Pt:Siero:Ord:IF Synonyms: anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	purkinjecellen type 2 As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie Synonyms: antistof; antilichaam IF soort
pl-PL	Polish (Poland)	Cytoplazmatyczne typu 2 komórek Purkinjego Ab:granica wykrywalności:punkt w czasie:surowica:półilościowy:immunofluorescencja Synonyms: PCA-2 Przeciwciała typu 1 do cytoplazmy komórki Purkinjego
ru-RU	Russian (Russian Federation)	Пуркинье клетки тип 2 Ат:PrThr:ТчкВрм:Сыв:Пор:ИФ Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Purkinje hücreleri tip 2 Ab:MevcEşik:Zmlı:Ser:Srl:IF Synonyms: Ak İmmünflorerans Mevcut
zh-CN	Chinese (China)	浦肯雅细胞胞浆 2 型抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法 Synonyms: 2 型 Purkinje 细胞 Ab 2 型 Purkinje 细胞抗体 2 型朴金耶细胞 Ab 2 型朴金耶细胞抗体 2 型浦肯雅细胞 Ab 2 型浦肯雅细胞抗体 2 型浦金埃细胞 Ab 2 型浦金埃细胞抗体 Ⅱ Ab;自身抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 II Purkinje 细胞 2 型 Ab Purkinje 细胞 2 型抗体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间朴金耶细胞 2 型 Ab 朴金耶细胞 2 型抗体浦肯雅细胞 2 型 Ab 浦肯雅细胞胞浆（细胞浆、细胞质、胞质） 2 型;浦肯雅细胞 2 型;2 型 Purkinje 细胞;2 型朴金耶细胞;2 型浦肯雅细胞;2 型浦金埃细胞;Purkinje 细胞 2 型;朴金耶细胞 2 型;浦金埃细胞 2 型浦金埃细胞 2 型 Ab 浦金埃细胞 2 型抗体细胞浆的;细胞质;细胞质的;胞浆;胞浆的血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.