LOINC
Version 2.67

84925-7PCA-2 Ab [Presence] in Serum by ImmunofluorescenceActive

Term Description

Antineuronal antibodies against PCA-2 are detected and characterized based on immunofluorescence staining pattern on multiple neuronal, non-neuronal tissues, and transformed substrate cells.
Source: Regenstrief LOINC

Part Description

LP31708-8   Purkinje cell cytoplasmic type 2
Anti-PCA-2 (purkinje cell cytoplasmic antibody type 2) autoantibodies are important markers of neurological autoimmunity related to cancer. PCA-2 binds to cerebellar Purkinje somata and dendrites, neurons in internal granular layer and dentate nucleus, and neuronal elements in gut and kidney. Patients present with mixed subacute neurological diorders, including brainstem or limbic encephalitis, cerebellar ataxia, Lambert-Eaton myasthenic syndrome, and autonomic and motor neuropathy. Patients with symptoms of such disorders, especially those with known risk factors for cancer, will undergo testing for paraneoplastic antibodies, including PCA-2. Testing is also performed to monitor the immune response of seropositive patients in the course of cancer therapy. [PMID: 10716248] Source: Regenstrief LOINC, Cytoplasmic

Fully-Specified Name

Component
Purkinje cell cytoplasmic type 2 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
PCA-2 Ab Ser Ql IF
Display Name
PCA-2 Ab IF Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
浦肯雅细胞胞浆 2 型 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
nl-NLDutch (NETHERLANDS)
purkinjecellen type 2 As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
fr-BEFrench (BELGIUM)
Cellules de Purkinje type 2 Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-CAFrench (CANADA)
Cellules de Purkinje cytoplasmique type 2 , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-FRFrench (FRANCE)
APCA-2 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
de-ATGerman (AUSTRIA)
PCA-2 AK ql.
it-ITItalian (ITALY)
Cellule di Purkinje tipo 2 , Ab:PrThr:Pt:Siero:Ord:IF
ru-RURussian (RUSSIAN FEDERATION)
Пуркинье клетки тип 2 Ат:PrThr:ТчкВрм:Сыв:Пор:ИФ
es-ESSpanish (SPAIN)
Células de Purkinje tipo 2 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
tr-TRTurkish (TURKEY)
Purkinje hücreleri tip 2 Ab:MevcEşik:Zmlı:Ser:Srl:IF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=84925-7