Version 2.77

Term Description

Antineuronal antibodies against PCA-Tr are detected and characterized based on immunofluorescence staining pattern on multiple neuronal, non-neuronal tissues, and transformed substrate cells.
Source: Regenstrief LOINC

Part Descriptions

LP31709-6   Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264 Source: Regenstrief LOINC

LP39528-2   Purkinje cell cytoplasmic type Tr Ab
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264 Source: Regenstrief LOINC

Fully-Specified Name

Component
Purkinje cell cytoplasmic type Tr Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
PCA-Tr Ab Ser Ql IF
Display Name
PCA-Tr Ab IF Ql (S)
Consumer Name Alpha Get Info
PCA-Tr antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
9155

Member of these Groups Get Info

LOINC Group Group Name
LG29451-8 Purkinje cell cytoplasmic type Tr Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Células de Purkinje tipo Tr Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Citoplasma de células de Purkinje tipo Tr Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
fr-CA French (Canada) Cellules de Purkinje cytoplasmique type Tr , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-FR French (France) Tr anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Cellules de Purkinje type TR Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
Synonyms: Anticorps
it-IT Italian (Italy) Cellule di Purkinje tipo Tr Ab:PrThr:Pt:Siero:Ord:IF
Synonyms: anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) purkinjecellen type Tr As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF soort
pl-PL Polish (Poland) Cytoplazmatyczne typu Tr komórek Purkinjego Ab:granica wykrywalności:punkt w czasie:surowica:półilościowy:immunofluorescencja
Synonyms: Przeciwciała typu Tr do cytoplazmy komórki Purkinjego
ru-RU Russian (Russian Federation) Пуркинье клетки тип Tr Ат:PrThr:ТчкВрм:Сыв:Пор:ИФ
Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Purkinje hücreleri tip Tr Ab:MevcEşik:Zmlı:Ser:Srl:IF
Synonyms: Ak İmmünflorerans Mevcut
zh-CN Chinese (China) 浦肯雅细胞胞浆 Tr 型 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ab;自身抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 Purkinje 细胞 Tr 型 Ab Purkinje 细胞 Tr 型抗体 Tr 型 Purkinje 细胞 Ab Tr 型 Purkinje 细胞抗体 TR 型朴金耶细胞 Ab TR 型朴金耶细胞抗体 TR 型浦肯雅细胞 Ab TR 型浦肯雅细胞抗体 TR 型浦金埃细胞 Ab TR 型浦金埃细胞抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 朴金耶细胞 Tr 型 Ab 朴金耶细胞 Tr 型抗体 浦肯雅细胞 Tr 型 Ab 浦肯雅细胞 Tr 型抗体 浦金埃细胞 Tr 型 Ab 浦金埃细胞 Tr 型抗体 细胞浆的;细胞质;细胞质的;胞浆;胞浆的 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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