Version 2.77

Term Description

Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1 (AMPAR1) antibodies are detected and characterized based on immunofluorescence staining pattern on multiple neuronal, non-neuronal tissues, and transformed substrate cells.
Source: Regenstrief LOINC

Part Description

LP229976-8   Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor 1 (AMPAR1) and AMPA receptor 2 (AMPAR2) antibodies target the AMPA receptor, an ionotropic glutamate receptor and key excitatory neurotransmitter. AMPA receptors are comprised of different combinations of four glutamate receptor subunits called GluA1-GluA4 (also known as GluR1-GluR4 and GluR-A to GluR-D). They are vital for brain development and function, such as memory and cognitive development. Detection of antineuronal autoantibodies against AMPA receptors aids in the diagnosis of autoimmune encephalopathies, especially limbic encephalitis, and related conditions. PMCID: PMC4478035 The presence of AMPA antibodies may also indicate an undiscovered tumor in the thymus, lung or breast. PMID: 23983888 The neurological symptoms associated with AMPA receptor 1 antibodies include altered mental status, convulsions, memory loss amnesia, auditory hallucinations, limbic encephalitis, abnormal behavior, schizophrenia, dizziness and hyperthermia. The neurological symptoms associated with AMPA receptor 2 antibodies include seizures, short-term memory loss, limbic encephalitis, altered mental status, chorea and facial dyskinesia. PMID: 24707504 Source: Regenstrief LOINC

Fully-Specified Name

Component
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
AMPAR1 Ab Ser Ql IF
Display Name
AMPAR1 Ab IF Ql (S)
Consumer Name Alpha Get Info
AMPAR1 antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
14022

Member of these Groups Get Info

LOINC Group Group Name
LG50947-7 Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1 Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Receptor 1 de Alfa-amino-3-hidroxi-5-metil-4-isoxazolepropionato Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Receptor 1 Ab de alfa-amino-3-hidroxi-5-metil-4-isoxazolpropionato:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
fr-FR French (France) AMPA récepteur 1 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
it-IT Italian (Italy) Recettore tipo 1 per alfa-amino-3-idrossi-5metil-4-isoxazolepropionato Ab:PrThr:Pt:Siero:Ord:IF
Synonyms: AMPAR1 anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) alfa-amino-3-hydroxy-5-methyl-4-isoxazolpropionaatreceptor 1 As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF
zh-CN Chinese (China) Alpha-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体 1 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ⅰ Ⅲ Ab;自身抗体 Alpha-氨基-3-羟基-5-甲基-4-异恶唑丙酸受体 1;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 1;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 1;AMPAR1 Hydroxy I IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 III OH α 三 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 羟 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类 阿尔法

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=84929-9