Version 2.78

Term Description

This term is used to report the presence or absence of extended spectrum beta-lactamase (ESBL) enzymes based on inhibitory concentrations of cefepime and cefepime+clavulanate. This term was created for, but is not limited in use to, bioMerieux's ETEST ESBL assay.
Source: Regenstrief LOINC

Part Descriptions

LP232454-1   Extended-spectrum beta lactamase by cefepime to cefepime+clavulanate inhibitory concentration ratio
Extended spectrum beta-lactamase (ESBL) enzymes are resistance enzymes produced by pathogenic organisms such as E. coli and Klebsiella. The presence of ESBLs can be detected by comparing the inhibitory concentration (IC) of a specific antimicrobial, such as cefepime (a 4th generation cephalosporin), cefotaxime, or ceftazidime (both 3rd generation cephalosporins), with the IC of that antimicrobial plus clavulanate, an ESBL inhibitor. Source: Regenstrief LOINC

LP234471-3   Gradient strip ARD
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component
Extended-spectrum beta lactamase by cefepime to cefepime+clavulanate inhibitory concentration ratio
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
Gradient strip ARD

Additional Names

Short Name
ESBL cefep + cefep-clav IC Islt Ql Grad
Display Name
ESBL by cefepime to cefepime-clavulanate IC ratio ARD gradient strip Ql (Isol)
Consumer Name Alpha Get Info
ESBL by Cefepime to Cefepime-clavulanate IC Ratio

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) ESBL para la concentración inhibitoria de cefepime frente a la de cefepime-clavulanico:PrThr:Punto temporal:Aislado:Ord:Detercción de resistencia antimicrobiana por gradiente en tira.
es-MX Spanish (Mexico) Relación de concentración inhibidora de betalactamasa de espectro extendido por cefepima a cefepima + clavulanato:Presencia o umbral:Punto temporal:Aislado:Ordinal:Tira degradada para la detección de resistencia a los antimicrobianos
fr-FR French (France) Ratio CMI bêta lactamase à spectre élargi céfépime/céfépime+clavulanate:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Bandelette graduée ARD
it-IT Italian (Italy) Rapporto della concentrazione inibitoria di cefepime/cefepime e acido clavulanico, beta-lattamici a largo spettro:PrThr:Pt:Isolato:Ord:Striscia di gradiente ARD
Synonyms: Gradiente striscia (E-test) Presenza o Soglia Punto nel tempo (episodio) Rapporto della IC del cefepime/cefepime e acido cl Striscia di gradiente per detezione resistenza ant Suscettibilità agli antibiotici
zh-CN Chinese (China) 头孢吡肟相对于头孢吡肟+克拉维酸抑菌浓度比值法超广谱 beta 内酰胺酶:存在情况或阈值:时间点:分离株:序数型:抗生素耐药性检测梯度胶条法
Synonyms: ARD 梯度胶条法;E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条;ARD;antimicrobial resistance detection B Betalactamase Beta-内酰胺酶 B-Lactamase B-内酰胺酶 ESBL;头孢吡肟+棒酸 E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条 β β内酰胺酶 β-内酰胺酶 β-内酰胺酶抑制剂;棒酸 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 头孢吡肟相对于（与、相对）头孢吡肟+克拉维酸（棒酸）抑菌浓度（抑制浓度、IC）比值（比例、比、比率）法超广谱 beta 内酰胺酶（超广谱β内酰胺酶、超广谱β-内酰胺酶、ESBL）;头孢吡肟相对于头孢吡肟+克拉维酸抑菌浓度比值法 ESBL 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 贝塔

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85043-8