85043-8

ESBL by cefepime to cefepime-clavulanate IC ratio [Presence] by ARD gradient strip

Active

Term Description

This term is used to report the presence or absence of extended spectrum beta-lactamase (ESBL) enzymes based on inhibitory concentrations of cefepime and cefepime+clavulanate. This term was created for, but is not limited in use to, bioMerieux's ETEST ESBL assay.

Part Descriptions

LP232454-1 Extended-spectrum beta lactamase by cefepime to cefepime+clavulanate inhibitory concentration ratio
Extended spectrum beta-lactamase (ESBL) enzymes are resistance enzymes produced by pathogenic organisms such as E. coli and Klebsiella. The presence of ESBLs can be detected by comparing the inhibitory concentration (IC) of a specific antimicrobial, such as cefepime (a 4th generation cephalosporin), cefotaxime, or ceftazidime (both 3rd generation cephalosporins), with the IC of that antimicrobial plus clavulanate, an ESBL inhibitor. Source: Regenstrief LOINC

LP234471-3 Gradient strip ARD
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Extended-spectrum beta lactamase by cefepime to cefepime+clavulanate inhibitory concentration ratio:PrThr:Pt:Isolate:Ord:Gradient strip ARD
Long Common Name: ESBL by cefepime to cefepime-clavulanate IC ratio [Presence] by ARD gradient strip
Short Name: ESBL cefep + cefep-clav IC Islt Ql Grad
Display Name: ESBL by cefepime to cefepime-clavulanate IC ratio ARD gradient strip Ql (Isol)
Consumer Name Alpha Get Info: ESBL by Cefepime to Cefepime-clavulanate IC Ratio

Part Model Get Info

Component
Extended-spectrum beta lactamase by cefepime to cefepime+clavulanate inhibitory concentration ratio
LP232454-1
- Analyte
  Extended-spectrum beta lactamase by cefepime to cefepime+clavulanate inhibitory concentration ratio
  LP232454-1
  - Component Numerator
    Extended-spectrum beta lactamase by cefepime to cefepime+clavulanate inhibitory concentration ratio
    LP232454-1
    - Component Numerator Core
      Extended-spectrum beta lactamase by cefepime to cefepime+clavulanate inhibitory concentration ratio
      LP232454-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate
LP7370-2
- System Core
  Isolate
  LP7370-2
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Gradient strip ARD
LP234471-3

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.58 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	ESBL pomocí poměru inhibiční koncentrace cefepimu k cefepim-klavulanátu:Přítomnost nebo práh:Časový bod:Izolát:Ordinální:Testovací proužek s gradientem k detekci antimikrobiální rezistence
el-GR	Greek (Greece)	Αναλογία ανασταλτικής συγκέντρωσης β-λακταμάσης εκτεταμένου φάσματος από κεφεπίμη προς κεφεπίμη+κλαβουλανικό:PrThr:Pt:Απομονωμένο στέλεχος:Ord:Λωρίδα με διαβαθμίσεις ARD Synonyms: ABXBACT Kλαβουλανικό Ord PrThr Pt Αναλογία ανασταλτικής συγκέντρωσης β-λακταμάσης εκτεταμένου φάσματος από κεφεπίμη προς κεφεπίμη+κλαβουλανικό Απομονωμένο στέλεχος Βήτα λακταμάση Κεφεπίμη Κεφεπίμη+Kλαβουλανικό Λωρίδα με διαβαθμίσεις Λωρίδα με διαβαθμίσεις ARD
es-ES	Spanish (Spain)	ESBL para la concentración inhibitoria de cefepime frente a la de cefepime-clavulanico:PrThr:Punto temporal:Aislado:Ord:Detercción de resistencia antimicrobiana por gradiente en tira.
es-MX	Spanish (Mexico)	Relación de concentración inhibidora de betalactamasa de espectro extendido por cefepima a cefepima + clavulanato:Presencia o umbral:Punto temporal:Aislado:Ordinal:Tira degradada para la detección de resistencia a los antimicrobianos
fr-FR	French (France)	Ratio CMI bêta lactamase à spectre élargi céfépime/céfépime+clavulanate:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Bandelette graduée ARD
it-IT	Italian (Italy)	Rapporto della concentrazione inibitoria di cefepime/cefepime e acido clavulanico, beta-lattamici a largo spettro:PrThr:Pt:Isolato:Ord:Striscia di gradiente ARD Synonyms: Gradiente striscia (E-test) Presenza o Soglia Punto nel tempo (episodio) Rapporto della IC del cefepime/cefepime e acido cl Striscia di gradiente per detezione resistenza ant Suscettibilità agli antibiotici
pl-PL	Polish (Poland)	Beta laktamazy o rozszerzonym-spektrum przez cefepim do cefepimu+kwas klawulanowy wskaźnik stężenia hamującego:granica wykrywalności:punkt w czasie:izolat:uporządkowany:pasek gradientowy na środki przeciwdrobnoustrojowe Synonyms: Wskaźnik stężenia hamującego beta-laktamazy o rozszerzonym spektrum działania (ESBL) przez cefepim i mieszaninę cefepimu z kwasem klawulanowym β-laktamaza
zh-CN	Chinese (China)	头孢吡肟相对于头孢吡肟+克拉维酸抑菌浓度比值法超广谱 beta 内酰胺酶:存在情况或阈值:时间点:分离株:序数型:抗生素耐药性检测梯度胶条法 Synonyms: ARD 梯度胶条法;E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条;ARD;antimicrobial resistance detection B Betalactamase Beta-内酰胺酶 B-Lactamase B-内酰胺酶 ESBL;头孢吡肟+棒酸 E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条 β β内酰胺酶 β-内酰胺酶 β-内酰胺酶抑制剂;棒酸依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分离物;分离菌;分离菌株;隔离种群头孢吡肟相对于（与、相对）头孢吡肟+克拉维酸（棒酸）抑菌浓度（抑制浓度、IC）比值（比例、比、比率）法超广谱 beta 内酰胺酶（超广谱β内酰胺酶、超广谱β-内酰胺酶、ESBL）;头孢吡肟相对于头孢吡肟+克拉维酸抑菌浓度比值法 ESBL 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类时刻;随机;随意;瞬间贝塔

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.